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beta-Thalassemia

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Definition: A disorder characterized by reduced synthesis of the beta chains of hemoglobin. There is retardation of hemoglobin A synthesis in the heterozygous form (thalassemia minor), which is asymptomatic, while in the homozygous form (thalassemia major, Cooley's anemia, Mediterranean anemia, erythroblastic anemia), which can result in severe complications and even death, hemoglobin A synthesis is absent.  delta-beta thalassemia    Other names Thalassemia Minor; Thalassemia Major; Hemoglobin F Disease; Anemia, Mediterranean; Anemia, Erythroblastic; Anemia, Cooley's; beta Thalassemia; Thalassemia Minors (beta-Thalassemia Minor); Thalassemia Minor (beta Thalassemia Minor); Thalassemia Majors (beta-Thalassemia Major); Thalassemia Major (beta Thalassemia Major); Thalassemia Intermedias; Minors, Thalassemia (beta-Thalassemia Minor); Minor, Thalassemia (beta-Thalassemia Minor); Mediterranean Anemia; Majors, Thalassemia (beta-Thalassemia Major); Major, Thalassemia (beta-Thalassemia Major); Intermedias, Thalassemia; Intermedia, Thalassemia; Erythroblastic Anemia

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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