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Nevus, Epithelioid and Spindle Cell

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Definition: A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumor presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in color from pink-tan to purplish red, often with surface telangiectasia. (Dorland, 27th ed)  /blood supply /chem /secret /ultrastruct permitted; coord IM with SKIN NEOPLASMS (IM) + site (IM or NIM) if relevant    Other names Spitz Nevus; Nevus, Spindle Cell and Epithelioid; Nevus, Spitz

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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