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Codon, Terminator

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Definition: Any codon that signals the termination of genetic translation (TRANSLATION, GENETIC). PEPTIDE TERMINATION FACTORS bind to the stop codon and trigger the hydrolysis of the aminoacyl bond connecting the completed polypeptide to the tRNA. Terminator codons do not specify amino acids.     
See Also Peptide Chain Termination, Translational; Protein Biosynthesis
Examples Codon, Nonsense 		Other names Terminator Codon; Stop Codon; Codon, Stop; Codon, Opal Stop; Codon, Ochre Stop; Codon, Amber Stop; Amber Stop Codon; UGA, Stop Codon; UGA Stop Codons; UGA Codons; UAG, Stop Codon; UAG Stop Codons; UAG Codons; UAA, Stop Codon; UAA Stop Codons; UAA Codons; Translation Stop Signals; Translation Stop Signal; Terminator Codons, Amber; Terminator Codons

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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