Definition: Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).
prion proteins; PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS; /pathogen permitted; DF: PRPSC
ExamplesPrP 27-30 Protein