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PrPSc Proteins

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Definition: Abnormal isoform of prion proteins (PRIONS) resulting from a posttranslational modification of the cellular prion protein (PRPC PROTEINS). PrPSc are disease-specific proteins seen in certain human and animal neurodegenerative diseases (PRION DISEASES).  prion proteins; PrPSc stands for PRion Protein SCrapie; do not confuse with PRPC PROTEINS; /pathogen permitted; DF: PRPSC   
Examples PrP 27-30 Protein 		Other names PrP res; Sp 33-35; Scrapie Virus; Scrapie PrP 33-35; Scrapie HaSp33-37 Protein; PrP-res; PrP 33-35; PrP (CJD); PrP (GSS); Scrapie PrP; Scrapie Agent; HaSp 33-37

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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