Definition: Mice selectively bred for hypersusceptibility to two-stage chemical skin carcinogenesis. They are also hypersusceptible to UV radiation tumorigenesis with single high-dose, but not chronic low-dose, exposures. SENCAR (SENsitive to CARcinogenesis) mice are used in research as an animal model for tumor production.
NIM when exper animal: no qualif; when IM, qualif permitted; do not forget also to check tag MICE; SENCAR stands for SENsitive to CARcinogenesis
