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Landau-Kleffner Syndrome

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Definition: A syndrome characterized by the onset of isolated language dysfunction in otherwise normal children (age of onset 4-7 years) and epileptiform discharges on ELECTROENCEPHALOGRAPHY. Seizures, including atypical absence (EPILEPSY, ABSENCE), complex partial (EPILEPSY, COMPLEX PARTIAL), and other types may occur. The electroencephalographic abnormalities and seizures tend to resolve by puberty. The language disorder may also resolve although some individuals are left with severe language dysfunction, including APHASIA and auditory AGNOSIA. (From Menkes, Textbook of Child Neurology, 5th ed, pp749-50; J Child Neurol 1997 Nov;12(8):489-495)     
See Also Aphasia
Other names Syndrome, Landau-Kleffner; Landau Kleffner Syndrome; Landau Kleffner Acquired Epileptiform Aphasia; Epileptiform Aphasias, Acquired; Epileptiform Aphasia, Acquired; Epileptic Aphasias, Acquired; Epileptic Aphasia, Acquired; Acquired Epileptiform Aphasias; Acquired Epileptic Aphasias; Acquired Epileptic Aphasia; Landau-Kleffner Acquired Epileptiform Aphasia; Aphasia, Epileptic, Acquired; Acquired Epileptiform Aphasia; Acquired Aphasia with Convulsive Disorder; Aphasia, Acquired Epileptic; Acquired Childhoood Aphasia with Convulsive Disord

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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