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DNA Footprinting

More information in Books or onNLM PubMed
Definition: A method for determining the sequence specificity of DNA-binding proteins. DNA footprinting utilizes a DNA damaging agent (either a chemical reagent or a nuclease) which cleaves DNA at every base pair. DNA cleavage is inhibited where the ligand binds to DNA. (from Rieger et al., Glossary of Genetics: Classical and Molecular, 5th ed)  DNA FINGERPRINTING is available    Other names Footprintings, DNA; Footprinting, DNA; Footprint, DNA; DNA Footprints; DNA Footprintings; DNA Footprint; Footprints, DNA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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