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Prostatic Intraepithelial Neoplasia

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Definition: A premalignant change arising in the prostatic epithelium, regarded as the most important and most likely precursor of prostatic adenocarcinoma. The neoplasia takes the form of an intra-acinar or ductal proliferation of secretory cells with unequivocal nuclear anaplasia, which corresponds to nuclear grade 2 and 3 invasive prostate cancer.  /blood supply /chem /second /secret /ultrastruct permitted; coord IM with PROSTATIC NEOPLASMS (IM); DF: PROSTATIC INTRAEPITHELIAL NEOPL    Other names Prostatic Neoplasia, Intraepithelial; Prostatic Intraepithelial Neoplasm; Prostatic Intraepithelial Neoplasias; Neoplasms, Prostatic Intraepithelial; Neoplasm, Prostatic Intraepithelial; Neoplasia, Intraepithelial Prostatic; Intraepithelial Prostatic Neoplasias; Intraepithelial Neoplasms, Prostatic; Intraepithelial Neoplasm, Prostatic; Intraepithelial Neoplasia, Prostatic; Prostatic Intraepithelial Neoplasms; Intraepithelial Prostatic Neoplasia; Neoplasia, Prostatic Intraepithelial

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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