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Comet Assay

More information in Books or onNLM PubMed
Definition: A genotoxicological technique for measuring DNA damage in an individual cell using single-cell gel electrophoresis. Cell DNA fragments assume a "comet with tail" formation on electrophoresis and are detected with an image analysis system. Alkaline assay conditions facilitate sensitive detection of single-strand damage.     
See Also DNA Damage 		Other names Single-Cell Gel Electrophoresis; Single-Cell Gel Electrophoreses; Gel Electrophoresis, Single Cell; Gel Electrophoreses, Single-Cell; Electrophoresis, Single-Cell Gel; Electrophoreses, Single-Cell Gel; Comet Assays, Alkaline; Comet Assays; Comet Assay, Alkaline; Assays, Comet; Assays, Alkaline Comet; Assay, Comet; Assay, Alkaline Comet; Alkaline Single Cell Gel Electrophoresis Assay; Alkaline Comet Assays; Gel Electrophoresis, Single-Cell; Electrophoresis, Gel, Single-Cell; Alkaline Single-Cell Gel Electrophoresis Assay; Alkaline Comet Assay

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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