Definition: Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995).
Other names v-myb Oncogene; v-myb Gene; v myb Oncogenes; v myb Genes; myb Oncogenes; myb Gene; c-myb Proto-Oncogene; c-myb Gene; c myb Proto Oncogenes; c myb Genes; Proto-Oncogenes, c-myb; Proto-Oncogene, c-myb; Oncogenes, v-myb; Oncogenes, myb; Oncogene, v-myb; Oncogene, myb; Genes, v-myb; Genes, c-myb; Gene, v-myb; Gene, c-myb
