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Maximum Tolerated Dose

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Definition: The highest dose of a biologically active agent given during a chronic study that will not reduce longevity from effects other than carcinogenicity. (from Lewis Dictionary of Toxicology, 1st ed)      Other names Tolerated Doses, Maximum; Tolerated Doses, Maximally; Tolerated Doses, Maximal; Tolerated Dose, Maximum; Tolerated Dose, Maximally; Tolerated Dose, Maximal; Maximum Tolerated Doses; Maximally Tolerated Doses; Maximal Tolerated Doses; Doses, Maximum Tolerated; Doses, Maximally Tolerated; Doses, Maximal Tolerated; Dose, Maximum Tolerated; Dose, Maximally Tolerated; Dose, Maximal Tolerated; Maximally Tolerated Dose; Maximal Tolerated Dose

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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