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Receptor, erbB-3

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Definition: A cell surface protein-tyrosine kinase receptor that is specific for NEUREGULINS. It has extensive homology to and can heterodimerize with the EGF Receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR) and the erbB-2 receptor (RECEPTOR, ERBB-2). Overexpression of the erbB-3 receptor is associated with tumorigenesis.      Other names erbB-3, Proto-Oncogene Proteins; erbB-3, Proto-Oncogene Protein; erbB-3 Receptor; erbB 3 Protein; c-erbB-3, Proto-Oncogene Protein; c erbB 3 Protein; Receptor, erbB 3; Proto-Oncogene Protein, HER-3; Proto Oncogene Proteins erbB 3; Proto Oncogene Protein erbB 3; Proto Oncogene Protein c erbB 3; HER 3 Proto Oncogene Protein; Proto-Oncogene Proteins erbB-3; Proto-Oncogene Protein c-erbB-3; erbB-3 Protein; c-erbB-3 Protein; Proto-Oncogene Protein erbB-3; HER-3 Proto-Oncogene Protein

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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