Definition: DNA constructs that are composed of, at least, all elements, such as a REPLICATION ORIGIN; TELOMERE; and CENTROMERE, required for successful replication, propagation to and maintainance in progeny human cells. In addition, they are constructed to carry other sequences for analysis or gene transfer.
coord with specific human chromosome /genet only if particularly discussed
Other names Human Artificial Chromosome; Chromosome, Human Artificial; Artificial Chromosome, Human; HACs (Chromosomes); HAC (Chromosome); Chromosomes, Human Artificial; Human Artificial Chromosomes; Artificial Chromosomes, Human
