encyclopedia of medical concepts
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 
ψ 

Complementarity Determining Regions

More information in Books or onNLM PubMed
Definition: Three regions (CDR1; CDR2 and CDR3) of amino acid sequence in the IMMUNOGLOBULIN VARIABLE REGION that are highly divergent. Together the CDRs from the light and heavy immunoglobulin chains form a surface that is complementary to the antigen. These regions are also present in other members of the immunoglobulin superfamily, for example, T-cell receptors (RECEPTORS, ANTIGEN, T-CELL).     
See Also Receptors, Antigen, T-Cell 		Other names Third Complementarity-Determining Regions; Third Complementarity Determining Region; Regions, Immunoglobulin Hypervariable; Regions, Complementarity-Determining; Regions, Complementarity Determining; Region, Immunoglobulin Hypervariable; Region, Complementarity Determining; Immunoglobulin Hypervariable Regions; Immunoglobulin Hypervariable Region; Complementarity-Determining Regions, Third; Complementarity-Determining Regions; Complementarity-Determining Region, Third; Complementarity-Determining Region 3s; Third Complementarity-Determining Region; Hypervariable Regions, Immunoglobulin; Hypervariable Region, Immunoglobulin; Complementarity-Determining Region 3; Complementarity-Determining Region; Complementarity Determining Region III; Complementarity Determining Region II

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy