Definition: DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
Other names Sites, E-Box; Site, E-Box; Sequences, E-Box; Sequence, E-Box; Motifs, E-Box; Motif, E-Box; Elements, E-Box; Element, E-Box; E-Box Site; E-Box Sequence; E-Box Motif; E-Box Element; E Box Sites; E Box Sequences; E Box Motifs; E Box Elements; E-Box Sites; E-Box Sequences; E-Box Motifs
