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Prokaryotic Initiation Factor-1

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Definition: The smallest of the three prokaryotic initiation factors with a molecular size of approximately 8 kD. It binds near the A-site of the 30S subunit of RIBOSOMES and may play a role in preventing premature addition of aminoacyl-tRNA-linked PEPTIDE ELONGATION FACTOR TU to the ribosome during the initiation of a peptide chain (PEPTIDE CHAIN INITIATION, TRANSLATIONAL).      Other names Prokaryotic Peptide Initiation Factor 1; Prokaryotic Initiation Factor 1; Peptide Initiation Factor IF 1; Peptide Initiation Factor 1, Prokaryotic; Initiation Factor-1, Prokaryotic; Initiation Factor IF 1; IF-1, Initiation Factor; Prokaryotic Peptide Initiation Factor-1; Peptide Initiation Factor-1, Prokaryotic; Initiation Factor IF-1; Peptide Initiation Factor IF-1

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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