Phosphatidylinositol Diacylglycerol-Lyase (definition)

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ψ ψ	Phosphatidylinositol Diacylglycerol-Lyase

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Definition: A phosphorus-oxygen lyase found primarily in BACTERIA. The enzyme catalyzes the cleavage of a phosphoester linkage in 1-phosphatidyl-1D-myo-inositol to form 1D-myo-inositol 1,2-cyclic phosphate and diacylglycerol. The enzyme was formerly classified as a phosphoric diester hydrolase (EC 3.1.4.10) and is often referred to as a TYPE C PHOSPHOLIPASES. However it is now known that a cyclic phosphate is the final product of this enzyme and that water does not enter into the reaction.

note X refs: TYPE C PHOSPHOLIPASES is also available

Other names Phosphodiesterase, Monophosphatidylinositol; Phosphodiesterase, 1-Phosphatidylinositol; Phosphatidylinositol Diacylglycerol Lyase; Diacylglycerol-Lyase, Phosphatidylinositol; 1 Phosphatidylinositol Phosphodiesterase; Monophosphatidylinositol Phosphodiesterase; 1-Phosphatidylinositol Phosphodiesterase

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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