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Genomic Islands

More information in Books or onNLM PubMed
Definition: Distinct units in some bacterial, bacteriophage or plasmid GENOMES that are types of MOBILE GENETIC ELEMENTS. Encoded in them are a variety of fitness conferring genes, such as VIRULENCE FACTORS (in "pathogenicity islands or islets"), ANTIBIOTIC RESISTANCE genes, or genes required for SYMBIOSIS (in "symbiosis islands or islets"). They range in size from 10 - 500 kilobases, and their GC CONTENT and CODON usage differ from the rest of the genome. They typically contain an INTEGRASE gene, although in some cases this gene has been deleted resulting in "anchored genomic islands".      Other names Symbiosis Islet; Symbiosis Island; Pathogenicity Islet; Pathogenicity Island; Islets, Pathogenicity; Islets, Symbiosis; Islets, Genomic; Islet, Symbiosis; Islet, Pathogenicity; Islet, Genomic; Islands, Symbiosis; Islands, Pathogenicity; Islands, Genomic; Islands, Anchored Genomic; Island, Symbiosis; Island, Pathogenicity; Island, Genomic; Island, Anchored Genomic; Genomic Islet; Genomic Islands, Anchored

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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