Matrix Attachment Regions (definition)

encyclopedia of medical concepts

ψ ψ	Matrix Attachment Regions

More information in Books or on

Definition: Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.

Other names Sequences, MRS; Scaffold-Attached Region; Scaffold Attachment Region; Scaffold Attached Regions; SAR Element; Regions, Scaffold-Attached; Regions, Scaffold Attachment; Regions, Matrix-Attached; Regions, Matrix Attachment; Region, Scaffold-Attached; Region, Scaffold Attachment; Region, Matrix-Attached; Region, Matrix Attachment; Matrix-Attached Region; Matrix Attachment Region; Matrix Attached Regions; MRS Sequences; MAR SAR Recognition Signature Sequence; Elements, SAR; Elements, MAR

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link

Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor

We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy