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Oncolytic Viruses

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Definition: Tumor-selective, replication competent VIRUSES that have antineoplastic effects. This is achieved by producing cytotoxicity-enhancing proteins and/or eliciting an antitumor immune response. They are genetically engineered so that they can replicate in CANCER cells but not in normal cells, and are used in ONCOLYTIC VIROTHERAPY.  ONCOGENIC VIRUSES is available   
See Also Oncolytic Virotherapy
Other names Viruses, Oncolytic; Virus, Oncolytic; Oncolytic Virus

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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