Definition: A large and highly glycosylated protein constituent of LIPOPROTEIN (A). It has very little affinity for lipids but forms disulfide-linkage to APOLIPOPROTEIN B-100. Apoprotein(a) has SERINE PROTEINASE activity and can be of varying sizes from 400- to 800-kDa. It is homologous to PLASMINOGEN and is known to modulate THROMBOSIS and FIBRINOLYSIS.
do not confuse with APOLIPOPROTEINS A, normal structural proteins of the alpha-lipoproteins (HIGH DENSITY LIPOPROTEINS)
Other names Protein, Antiangiogenic AK38; Apoprotein (a); Apolipoprotein(a); Apolipoprotein Lp(a+); Apolipoprotein (a); Antiangiogenic AK38 Protein; Apo Lp(a); Apolipoprotein Lp(a)
