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Receptors, OSM-LIF

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Definition: Cell surface receptors formed from the dimerization of LIF RECEPTOR ALPHA SUBUNIT with CYTOKINE RECEPTOR GP130. Although originally described as receptors for LEUKEMIA INHIBITORY FACTOR these receptors also bind the closely-related protein ONCOSTATIN M and are referred to as both LIF receptors and type I oncostatin M receptors.     
Examples Cytokine Receptor gp130; Leukemia Inhibitory Factor Receptor alpha Subunit 		Other names Receptors, OSM LIF; Receptors, LIF; Oncostatin M Leukemia Inhibitory Factor Shared Rec; OSM-LIF Receptors; Leukemia Inhibitory Factor Oncostatin M Shared Rec; Oncostatin M-Leukemia Inhibitory Factor Shared Rec; Oncostatin M Type I Receptor; Leukemia Inhibitory Factor-Oncostatin M Shared Rec; Leukemia Inhibitory Factor Receptors; LIF Receptors; Receptors, Leukemia Inhibitory Factor; Leukemia Inhibitory Factor Receptor

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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