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Microsatellite Instability

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Definition: The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.     
See Also Microsatellite Repeats 		Other names Replication Error Phenotypes; Phenotypes, Replication Error; Phenotype, Replication Error; Instability, Microsatellite; Error Phenotypes, Replication; Error Phenotype, Replication; Replication Error Phenotype

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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