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Nephrogenic Fibrosing Dermopathy

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Definition: A chronic, acquired, idiopathic, progressive eruption of the skin that occurs in the context of RENAL FAILURE. It is sometimes accompanied by systemic fibrosis. The pathogenesis seems to be multifactorial, with postulated involvement of circulating fibrocytes. There is a strong association between this disorder and the use of gadolinium-based contrast agents.      Other names Systemic Fibrosis, Nephrogenic; Systemic Fibroses, Nephrogenic; Nephrogenic Systemic Fibroses; Nephrogenic Fibrosing Dermopathies; Fibrosis, Nephrogenic Systemic; Fibrosing Dermopathy, Nephrogenic; Fibrosing Dermopathies, Nephrogenic; Fibroses, Nephrogenic Systemic; Dermopathy, Nephrogenic Fibrosing; Dermopathies, Nephrogenic Fibrosing; Nephrogenic Systemic Fibrosis

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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