Definition: Autosomal dominant syndrome characterized by cardiac and cutaneous MYXOMAS; LENTIGINOSIS (spotty pigmentation of the skin), and endocrinopathy and its associated endocrine tumors. The cardiac myxomas may lead to SUDDEN CARDIAC DEATH and other complications in Carney complex patients. The gene coding for the PRKAR1A protein is one of the causative genetic loci (type 1). A second locus is at chromosome 2p16 (type 2).
Other names Syndromes, NAME; Syndromes, LAMB; Syndrome, NAME; Syndrome, LAMB; Syndrome, Carney; NAME Syndromes; Myxoma-Endocrine Complex, Carney; LAMB Syndromes; Complex, Carney Myxoma-Endocrine; Complex, Carney; Carney Myxoma Endocrine Complex; Carney Complex, Type I; Carney Complex, Type 1; NAME Syndrome; Myxoma, Spotty Pigmentation, and Endocrine Overact; LAMB Syndrome; Carney Syndrome; Carney Myxoma-Endocrine Complex; Carney Complex, Type II; Carney Complex, Type 2
