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Thyrotropin Alfa

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Definition: A highly purified recombinant glycoprotein form of human THYROID-STIMULATING HORMONE, produced by recombinant DNA technology comprising two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites, and a beta subunit of 118 residues containing one N-linked glycosylation site. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.      Other names Thyrogen; TSH, Recombinant Human; Human TSH, Recombinant; Alfa, Thyrotropin; Recombinant Human TSH; Genzyme Brand of Thyrotropin Alfa; rhTSH

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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