Cell Cycle Checkpoints (definition)

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ψ	Cell Cycle Checkpoints

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Definition: Regulatory signaling systems that control the progression through the CELL CYCLE. They ensure that the cell has completed, in the correct order and without mistakes, all the processes required to replicate the GENOME and CYTOPLASM, and divide them equally between two daughter cells. If cells sense they have not completed these processes or that the environment does not have the nutrients and growth hormones in place to proceed, then the cells are restrained (or "arrested") until the processes are completed and growth conditions are suitable.

general; prefer specifics
See Also Cell Cycle Proteins; Genes, cdc
Examples G1 Phase Cell Cycle Checkpoints; G2 Phase Cell Cycle Checkpoints; M Phase Cell Cycle Checkpoints; S Phase Cell Cycle Checkpoints

Other names Point, Cell Cycle-Transition; Cycle-Transition Point, Cell; Controls, Cell Cycle; Control, Cell Cycle; Checkpoints, Cell Cycle; Checkpoint, Cell Cycle; Cell Cycle-Transition Point; Cell Cycle Controls; Cell Cycle Checkpoint; Cell Cycle Arrests; Arrests, Cell Cycle; Arrest, Cell Cycle; Cell Cycle-Transition Points; Cell Cycle Transition Points; Cell Cycle Control; Cell Cycle Arrest

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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