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Depressive Disorder, Treatment-Resistant

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Definition: Failure to respond to two or more trials of antidepressant monotherapy or failure to respond to four or more trials of different antidepressant therapies. (Campbell's Psychiatric Dictionary, 9th ed.)      Other names Treatment-Resistant Depressive Disorders; Treatment-Resistant Depressive Disorder; Treatment Resistant Depressions; Therapy-Resistant Depressions; Therapy Resistant Depression; Resistant Depressions, Treatment; Resistant Depression, Treatment; Refractory Depressions; Disorders, Treatment-Resistant Depressive; Disorder, Treatment-Resistant Depressive; Depressive Disorders, Treatment-Resistant; Depressive Disorder, Treatment Resistant; Depressions, Treatment Resistant; Depressions, Therapy-Resistant; Depressions, Refractory; Depression, Treatment Resistant; Depression, Therapy-Resistant; Depression, Refractory; Treatment Resistant Depression; Therapy-Resistant Depression

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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