Definition: The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
/blood: consider also HYPERTHYROXINEMIA
Other names T4 Thyroid Hormone; Levothyroxine; L-Thyroxine; Thyroid Hormone, T4; LevoT; Levo T; Leo, Tiroxina; LThyroxin beta; LThyroxin Henning; L Thyroxine Roche; L Thyroxine; L Thyroxin beta; L Thyroxin Henning; L Thyrox; Delalande, Levothyroxin; Deladande, Levothyroxin; Berlin Chemie Brand of Levothyroxine Sodium; betapharm Brand of Levothyroxine Sodium; Watson Brand of Levothyroxine Sodium; Vortex Brand of Levothyroxine Sodium
Med Klin 1980;75(1):35; Acta Physiol Pol 29(2):117;1978; Arzneim Forsch 1979;29(3):499; Arzneim Forsch 27(1):422;1977; Dtsch Med Wochenschr 15(11):815;1975; Fortschr Med 1979;97(42):1942; Med Klin 71(38):1555;1976; Med Welt 28(4):186;1977; Munch Med Wochenschr 120(21):739;1978; Verh Dtsch Ges Inn Med 82(2):874;1976; Verh Dtsch Ges Inn Med 83:392;1977; Wiad Lek 1979 32(14):987; Wiad Lek 1979;32(16):1135
