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7,8-dichloro-1,2,3,4-tetrahydroisoquinoline

under Tetrahydroisoquinolines
More information in Books or onNLM PubMed
More on Tetrahydroisoquinolines Definition: A group of ISOQUINOLINES in which the nitrogen containing ring is protonated. They derive from the non-enzymatic Pictet-Spengler condensation of CATECHOLAMINES with ALDEHYDES.      Other names Tetrahydro Isoquinolines; Tetrahydro-Isoquinolines; 1,2,3,4-Tetrahydroisoquinolines
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7,8-dichloro-1,2,3,4-tetrahydroisoquinoline [ DCTQ,SK&F 64139,SK&F-64139,SKF 64139 ]
  potent reversible inhibitor of phenylethanolamine N-methyltransferase; structure 		57987-77-6   *Tetrahydroisoquinolines Phenylethanolamine N-Methyltransferase/antagonists & inhibitors
Pharma Action Enzyme Inhibitors; Monoamine Oxidase Inhibitors 		Arch Pharm (Naun Schmiedeberg) 299(3):219;1977; Can J Biochem 55(7):761;1977; Clin Pharmacol Ther 25(6):837;1979; Enzyme 22(6):371;1977; J Pharmacol Exptl Therap 197(3):623;1976; Life Sci 21(2):261;1977; Naunyn Schmiedeberg Arch Pharm 295(2):127;1976; Naunyn Schmiedeberg Arch Pharm 297(3):245;1977; Res Cancer Chem Pathol Pharm 17(2):201;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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