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Monoamine Oxidase Inhibitors

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Definition: A chemically heterogeneous group of drugs that have in common the ability to block oxidative deamination of naturally occurring monoamines. (From Gilman, et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p414)  DF: MAO INHIB   
See Also Antidepressive Agents 		Other names Reversible Inhibitors of Monoamine Oxidase; MAO Inhibitors; Inhibitors, Monoamine Oxidase; Inhibitors, MAO; Inhibitor, Monoamine Oxidase; Reversible Inhibitor of Monoamine Oxidase; RIMA (Reversible Inhibitor of Monoamine Oxidase A); Monoamine Oxidase Inhibitor
Substances having this pharmacologic action: desmethylselegiline; cimoxatone; amezinium; amiflamine; rasagiline; brofaromine; milacemide; tribulin; 2-(3,4-dimethoxyphenyl)-3-fluoroallylamine; Moclobemide; pirlindole; Chlorphenamidine; Clorgyline; Nialamide; Selegiline; Tranylcypromine; Pargyline; Harmine; Furazolidone; Cuprizone; Harmaline; Phenelzine; Monocrotophos; Iproniazid; Isocarboxazid; toloxatone; 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline; Ro 41-1049; mofegiline; lazabemide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine  0   *Indoles *Piperidines Butyrylcholinesterase Cholinesterase Inhibitors Monoamine Oxidase Inhibitors. J Med Chem. 2011 Dec 22;54(24):8251-70.
6-methoxy-3-(4-methylphenyl)coumarin  0   *Coumarins Monoamine Oxidase Inhibitors. J Med Chem. 2011 Oct 27;54(20):7127-37.
N-(1-fluoro-3-phenylpropan-2-yl)-N-methylprop-2-yn-1-amine  0   Selegiline/*analogs & derivatives Fluorine Radioisotopes Monoamine Oxidase Inhibitors. J Med Chem. 2011 Oct 27;54(20):7023-9.
6-bromo-8-methoxy-3-(4'-methoxyphenyl)coumarin  0   *Coumarins Monoamine Oxidase Inhibitors. Bioorg Med Chem Lett 2011 Jul 15;21(14):4224-7
minaprine  25905-77-5 N-(4-methyl-6-phenyl-3-pyridazinyl)-4-morpholineethanamine  *Pyridazines Central Nervous System Stimulants Monoamine Oxidase Inhibitors.
Pharma Action Antidepressive Agents 		Agressologie 18(3):131;1977; Agressologie 18(5):257;1977; Probl Actuels Endocrinol Nutr 21:43;1977

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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