ψ 
Indoles 
  includes isoindoles   
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
DAPI  47165-04-8 2-(4-(aminoiminomethyl)phenyl)-1H-indole-6-carboximidamide  *Indoles. 
Pharma Action Fluorescent Dyes ; Intercalating Agents ; Trypanocidal Agents ; Serine Proteinase Inhibitors 		Acta Biochim Pol 1979;26(1-2):29; Anal Biochem 83:252;1977; Andrologia 10(5):329;1978; Andrologia 1978;10(5):329; Cancer Lett 4:89;1978; Cell Mol Biol 1979;25(2):137; Cell Mol Biol 1979;25(6):399; Cell Mol Biol 1979;25(6):429; Chromosoma 57(3):219;1976; Chromosoma 60(1):15;1977 complex with DNA; structure; Exp Cell Res 114(1):95;1978; Hautarzt 1979;30(8):434; Histochemistry 58(4):329;1978; Hum Genet 36(2):167;1977; J Cell Biol 1978;79(3):623; J Cell Biol 79(3):623;1978; J Cell Biol 82(1):299;1979; J Parasitol 1979;65(3):421; Med Dosw Mikrobiol 28(2):161;1976; Methods Cell Biol 12:337;1975
bisindolylmaleimide I  133052-90-1 1H-Pyrrole-2,5-dione, 3-(1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)  *Indoles *Maleimides Protein Kinase C/antagonists & inhibitors. 
Pharma Action Anti-Inflammatory Agents ; Enzyme Inhibitors 		J Biol Chem 1991;266(24):15771
fluvastatin  93957-54-1   *Fatty Acids, Monounsaturated *Indoles. 
Pharma Action Anticholesteremic Agents ; Hydroxymethylglutaryl-CoA Reductase Inhibitors 		Biochem Biophys Res Commun 1990;170(2):726LESCOL; LESCOL XL
cyclopiazonic acid  18172-33-3   *Indoles Calcium-Transporting ATPases/antagonists & inhibitors Mycotoxins. 
Pharma Action Anti-Arrhythmia Agents ; Enzyme Inhibitors ; Vasodilator Agents 		App Environ Microbiol 33(1):211;1977; Appl Environ Microbiol 1979;38(6):1052; Mycopathologia 1979;67(3):161; Mycopathologia 66(1-2):31;1978; Tetrahedron 24:201;1968
tropisetron  89565-68-4 1H-Indole-3-carboxylic acid, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, endo  *Indoles Anti-Arrhythmia Agents. 
Pharma Action Antiemetics ; Serotonin Antagonists 		Naunyn Schmiedebergs Arch Pharmacol 1985;329(1):36
Ro 31-8220  125314-64-9   *Indoles Protein Kinase C/antagonists & inhibitors. 
Pharma Action Enzyme Inhibitors ; Platelet Aggregation Inhibitors 		BIOCHEM BIOPHYS RES COMMUN 1990;169(3):1099
indo-1  96314-96-4 1H-Indole-6-carboxylic acid, 2-(4-(bis(carboxymethyl)amino)-3-(2-(2-(bis(carboxymethyl)amino)-5-methylphenoxy)ethoxy)phenyl)  *Indoles. 
Pharma Action Chelating Agents ; Fluorescent Dyes 		Soc Gen Physiol Ser 1986;40:327
trandolapril  87679-37-6   *Indoles. 
Pharma Action Angiotensin-Converting Enzyme Inhibitors ; Antihypertensive Agents 		Am J Cardiol 1987;59(10):12DMAVIK; TARKA; TRANDOLAPRIL
bisindolylmaleimide  119139-23-0   *Indoles *Maleimides Protein Kinase C/antagonists & inhibitors.  Am J Physiol 1994 Jun;266(6 Pt 2):H2159-66
indole  120-72-9   *Indoles.  J Biol Chem 1981;256(12):6348
indole-3-carbinol  700-06-1   *Indoles. 
Pharma Action Anticarcinogenic Agents 		Cancer Res 38:1410;1978; Food Cosmet Toxicol 16(2)(?)
L 663536  118414-82-7 1H-Indole-2-propanoic acid, 1-((4-chlorophenyl)methyl)-3-((1,1-dimethylethyl)thio)-alpha,alpha-dimethyl-5-(1-methylethyl)  *Indoles. 
Pharma Action Lipoxygenase Inhibitors 		Can J Physiol Pharmacol 1989;67(5):456
5-bromo-4-chloro-3-indolyl beta-galactoside  7240-90-6   *Galactosides *Indoles beta-Galactosidase. 
Pharma Action Chromogenic Compounds 		Histochem J 1984;16(12):1273
Go 6976  136194-77-9 12H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-12-propanenitrile, 5,6,7,13-tetrahydro-13-methyl-5-oxo  *Carbazoles *Indoles Protein Kinase C/antagonists & inhibitors. 
Pharma Action Enzyme Inhibitors 		J Biol Chem 1993 May 5;268(13):9194-7
phthalocyanine  574-93-6   *Indoles Pigments, Biological. 
Pharma Action Radiation-Sensitizing Agents 		J Bioenerg Biomembr 8(4):173;1976; J Bioenerg Biomembr 8(4):189;1976
ropinirole  91374-21-9   *Indoles. 
Pharma Action Antiparkinson Agents ; Dopamine Agonists 		J Med Chem 1985;28(10):1533REQUIP
copper phthalocyanine  147-14-8   *Indoles *Organometallic Compounds Copper. 
Pharma Action Coloring Agents ; Indicators and Reagents 		Eur J Biochem 52:567;1975; J Ultrastruct Res 1980;70(2):181; Vestn Rentgenol Radiol 114(2):97;1975
KT 5720  108068-98-0   *Carbazoles *Indoles *Pyrroles Protein Kinase C/antagonists & inhibitors Cyclic AMP-Dependent Protein Kinases/antagonists & inhibitors. 
Pharma Action Anti-Bacterial Agents ; Enzyme Inhibitors 		J Neurochem 1988;51(5):1565
FR 139317  142375-60-8 D-Alanine, N-(N-(N-((hexahydro-1H-azepin-1-yl)carbonyl)-L-leucyl)-1-methyl-D-tryptophyl)-3-(2-pyridinyl)  *Azepines *Indoles.  Mol Pharmacol 1993 Feb;43(2):127-31
KT 5823  126643-37-6 9,12-Epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylic acid, 2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-, methyl ester, (9R-(9alpha,10beta,12alpha))  *Carbazoles *Indoles Cyclic GMP-Dependent Protein Kinases/antagonists & inhibitors. 
Pharma Action Protein Kinase Inhibitors 		Res Commun Chem Pathol Pharmacol 1991 Oct;74(1):3-14
5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole  74163-68-1 Butanedioic acid, compd. with 5-methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole  *Indoles. 
Pharma Action Serotonin Agonists 		Eur J Pharmacol 1980;63(1):65
RP 67580  135911-02-3 4H-Isoindol-4-one, octahydro-2-(1-imino-2-(2-methoxyphenyl)ethyl)-7,7-diphenyl-, (3aR-cis)  *Indoles Receptors, Neurokinin-1/antagonists & inhibitors. 
Pharma Action Analgesics 		Proc Natl Acad Sci USA 1991;88(22):10208
SU 5416  0   *Indoles *Pyrroles Protein-Tyrosine Kinases/antagonists & inhibitors. 
Pharma Action Angiogenesis Inhibitors ; Protein Kinase Inhibitors 		Cancer Res 1999 Jan 1;59(1):99-106
tegaserod  145158-71-0   *Indoles. 
Pharma Action Gastrointestinal Agents ; Serotonin Agonists 		J Pharmacol Exp Ther 1997 Mar;280(3):1270-6ZELNORM
dolasetron mesylate  115956-13-3 1H-Indole-3-carboxylic acid, octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester, (2alpha,6alpha,8alpha,9abeta)-, monomethanesulfonate  *Indoles *Quinolizines. 
Pharma Action Antiemetics ; Serotonin Antagonists 		Eur J Pharmacol 1989;163(1):115ANZEMET
CC 1065  69866-21-3 Benzo(1,2-b:4,3-b')dipyrrole-3(2H)-carboxamide, 7-((1,6-dihydro-4-hydroxy-5-methoxy-7-((4,5,8,8a-tetrahydro-7-methyl-4-oxocyclopropa(c)pyrrolo(3,2-e)indol-2(1H)-yl)carbonyl)benzo(1,2-b:4,3-b')dipyrrol-3(2H)-yl)carbonyl)-1,6-dihydro-4-hydroxy-5-methoxy  *Indoles. 
Pharma Action Antibiotics, Antineoplastic 		J Antibiot (Tokyo) 1980;33(8):902; J Antibiot (Tokyo) 31(12):1211;1978
sertindole  106516-24-9   *Imidazoles *Indoles. 
Pharma Action Antipsychotic Agents 		Eur J Pharmacol 1990;182(3):613
PD 134308  130404-91-0   *Indoles Meglumine/*analogs & derivatives. 
Pharma Action Antineoplastic Agents ; Hormone Antagonists ; Anti-Anxiety Agents 		Proc Natl Acad Sci USA 1990;87(17):6728
tenidap  120210-48-2   *Indoles. 
Pharma Action Anti-Inflammatory Agents, Non-Steroidal ; Cyclooxygenase Inhibitors 		Arthritis Rheum 1990;33(1):29
indigo  482-89-3 2-(1,3- dihydro-3-oxo-2H-indol-2-ylidene)-1,2-dihydro- 3H-indol-3-one  *Indoles. 
Pharma Action Coloring Agents
Zn(II)-phthalocyanine  14320-04-8   *Indoles *Organometallic Compounds Zinc. 
Pharma Action Photosensitizing Agents 		J Inorg Biochem 1987;29(1):59
GR 113808  144625-51-4 1H-Indole-3-carboxylic acid, 1-methyl-, (1-(2-((methylsulfonyl)amino)ethyl)-4-piperidinyl)methyl ester  *Indoles *Sulfonamides. 
Pharma Action Serotonin Antagonists 		Br J Pharmacol 1993 Jul;109(3):618-24
aluminum tetrasulfophthalocyanine  122170-90-5   *Indoles *Organometallic Compounds. 
Pharma Action Antineoplastic Agents ; Fluorescent Dyes ; Radiation-Sensitizing Agents 		Cancer Lett 1986;30(3):321
methoxytryptophol  712-09-4   *Indoles. 
Pharma Action Anti-Anxiety Agents 		Arch Int Physiol Biochim 86(2):353;1978; Chronobiological Aspects Endocrinol W3C117H:386;1974C; Circ Res 44(5):723;1979; Endocrinology 98(2):482;1976; Horm Res 8:84;1977; J Chromatogr 112:523;1975; J Endocrinol 1979;82(2):243; J Endocrinol 1979;82(2):269; J Endocrinol 1979;83(1):35; J Endocrinol 1979;83(2):193; J Endocrinol 68(3):397;1976; J Neural Transm (Suppl) 13:279;1978; J Neural Transm (Suppl) 13:59;1978; J Neural Transm 33(3):12;1972; J Physiol (London)1979;291;49p; Life Sci 23(10):1019;1978; Nature 1979;282(5736):301; Psychoneuroendocrinology 1979;24(2):117
linopirdine  105431-72-9 2H-Indol-2-one, 1,3-dihydro-1-phenyl-3,3-bis(4-pyridinylmethyl)  *Indoles *Pyridines. 
Pharma Action Neuroprotective Agents ; Potassium Channel Blockers 		Br J Clin Pharmacol;28(1):1
perindoprilat  95153-31-4   *Indoles. 
Pharma Action Angiotensin-Converting Enzyme Inhibitors ; Cardiovascular Agents 		J Cardiovasc Pharmacol 1987;10(2):129
FK 888  138449-07-7 L-Alaninamide, trans-4-hydroxy-1-((1-methyl-1H-indol-3-yl)carbonyl)-L-prolyl-N-methyl-3-(2-naphthalenyl)-N-(phenylmethyl)  *Dipeptides *Indoles.  Br J Pharmacol 1992 Nov;107(3):785-9
indirubin  479-41-4   Indoles Leukemia, Myeloid, Chronic Protein Kinase Inhibitors. 
Pharma Action Antibiotics, Antineoplastic ; Coloring Agents 		Chung Kuo I Hsueh Ko Huseh Yuan Hsueh Pao 1980;2(2):83
ruboxistaurin  169939-94-0   *Indoles *Maleimides Protein Kinase C/antagonists & inhibitors. 
Pharma Action Enzyme Inhibitors 		Science 1996 May 3;272(5262):728-31
sunitinib  0   *Indoles *Pyrroles. 
Pharma Action Antineoplastic Agents ; Angiogenesis Inhibitors 		J Med Chem 2003 Mar 27;46(7):1116-9SUTENT
aluminum phthalocyanine  47822-79-7   *Indoles *Organometallic Compounds Aluminum.  Photochem Photobiol 1989;49(5):587
L 163191  0   *Indoles *Spiro Compounds.  Proc Natl Acad Sci U S A 1995 Jul 18;92(15):7001-5
aluminum phthalocyanine disulfonate  68637-19-4   *Indoles *Organometallic Compounds Aluminum. 
Pharma Action Fluorescent Dyes ; Radiation-Sensitizing Agents ; Photosensitizing Agents 		Photochem Photobiol 1990;51(3):379
5,6-dihydroxy-2-indolylcarboxylic acid  4790-08-3   *Indoles.  Sb Lek 1981;83(5):121
relcovaptan  150375-75-0   *Indoles *Pyrrolidines. 
Pharma Action Hormone Antagonists ; Platelet Aggregation Inhibitors 		J Clin Invest 1993 Jul;92(1):224-31
indolactam V  90365-57-4 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-, (2S-(2R*,5R*))  *Indoles *Lactams. 
Pharma Action Carcinogens 		Gann 1984;75(10):866
Indo-1 pentaacetoxymethyl ester  112926-02-0   *Indoles. 
Pharma Action Chelating Agents 		Cytometry 1989;10(2):165
5-hydroxyindole  1953-54-4   *Indoles.  Am J Dis Child 1980;134(9):838
rebeccamycin  93908-02-2 5H-Indolo(2,3-a)pyrrolo(3,4-c)carbazole-5,7(6H)-dione, 1,11-dichloro-12,13-dihydro-12-(4-O-methyl-beta-D-glucopyranosyl)  *Carbazoles *Indoles.  J Antibiot (Tokyo) 1987;40(5):668
chloroaluminum tetrasulfophthalocyanine  104469-80-9   *Indoles *Organometallic Compounds Aluminum. 
Pharma Action Photosensitizing Agents 		J Urol 1986;136(1):141
CY 208-243  100999-26-6 Indolo(4,3-ab)phenanthridine, 4,6,6a,7,8,12b-hexahydro-7-methyl-, trans-(-)  *Indoles *Phenanthridines. 
Pharma Action Antiparkinson Agents ; Dopamine Agonists 		Life Sci 1988;42(2):137
indolebutyric acid  133-32-4 1H-indole-3-butanoic acid  *Indoles.  In Vitro 13(1):41;1977
5,6-dihydroxyindole  3131-52-0   *Indoles Catechol O-Methyltransferase/antagonists & inhibitors. 
Pharma Action Enzyme Inhibitors 		J Med Chem 1982;25(3):263
perospirone  129273-38-7   *Indoles *Thiazoles. 
Pharma Action Antipsychotic Agents 		Jpn J Pharmacol 1990;53(3):321
paxilline  57186-25-1   *Indoles Mycotoxins Neurotoxins. 
Pharma Action Potassium Channel Blockers 		Fortschr Chem Org Naturst 1985;48:1
SB 206553  0   *Indoles *Pyridines. 
Pharma Action Serotonin Antagonists ; Anti-Anxiety Agents 		J Med Chem 1995 Jul 7;38(14):2524-30
3,3'-diindolylmethane  1968-05-4   *Indoles. 
Pharma Action Anticarcinogenic Agents 		Cancer Res 38:1410;1978
adozelesin  123219-86-3   *Cyclohexanecarboxylic Acids *Indoles *Cyclohexenes. 
Pharma Action Antineoplastic Agents, Alkylating 		Mutat Res 1989;223(2):129
SB 242084  0   *Aminopyridines *Indoles Receptors, Serotonin/antagonists & inhibitors.  Neuropharmacology 1997 Apr-May;36(4-5):609-20
PD 135158  130325-35-8   *Indoles Meglumine/*analogs & derivatives. 
Pharma Action Anti-Anxiety Agents 		Proc Natl Acad Sci USA 1990;87(17):6728
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