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Naphthalenes

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Definition: Two-ring crystalline hydrocarbons isolated from coal tar. They are used as intermediates in chemical synthesis, as insect repellents, fungicides, lubricants, preservatives, and, formerly, as topical antiseptics.  aromatic hydrocarbons   
Examples Acenaphthenes; Bunaftine; Carbaryl; Dansyl Compounds; Lovastatin; Naphthaleneacetic Acids; Naphthalenesulfonates; Naphthols; Naphthoquinones; 1-Naphthylamine; 2-Naphthylamine; 1-Naphthylisothiocyanate; Naphthylvinylpyridine; Pravastatin; Propranolol; Tetrahydronaphthalenes; Tolnaftate
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-(2'-naphthyl)-5-(2'-naphthyl)-2-acetyl-2,3-dihydro-1,3,4-oxadiazoline  0   *Naphthalenes *Oxazoles. Bioorg Med Chem. 2012 Jan 15;20(2):903-9.
orteronel  0   *Imidazoles *Naphthalenes. J Steroid Biochem Mol Biol. 2012 Apr;129(3-5):115-28
6-methyl-7-acetyl-1,8-dihydroxy naphthalene-1-O-beta-D(L)-glucoside  0   *Glucosides *Naphthalenes. Molecules. 2012;17(1) (dup#13):843-50
6-methyl-7-acetyl-1,8-dihydroxy-3-methoxy naphthalene-1-O-beta-D(L)-glucoside  0   *Glucosides *Naphthalenes. Molecules. 2012;17(1) (dup#13):843-50
eucleanal  0   *Naphthalenes. Nat Prod Commun. 2012 Feb;7(2):193-4
halowax 1051  0   *Hydrocarbons, Chlorinated *Naphthalenes. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2006;41(3):291-301.
2-hydroxy-1-naphthylidene-(8-aminoquinoline)  0   *Aminoquinolines *Naphthalenes. Luminescence. 2011 Nov-Dec;26(6):462-70
daurinol  0   *Naphthalenes *Benzodioxoles. Neoplasia. 2011 Nov;13(11):1043-57.
benz(cd)indol-2(1H)-one  0   *Lactams *Naphthalenes. Acta Crystallogr C. 2012 Jan;68(Pt 1):o1-6
naphthalenetetracarboxydiimide  0   *Imides *Naphthalenes. J Am Chem Soc. 2011 Nov 30;133(47):19056-9
6-methoxy-4-methyl-3, 4-dihydro-2H-naphthalen-1-one  0   *Naphthalenes. Yao Xue Xue Bao. 2010 Jan;45(1):82-6
6-((7-((1-aminocyclopropyl)methoxy)-6-methoxy-4-quinolyl)oxy)-N-methyl-naphthalene-1-carboxamide  0   *Naphthalenes *Quinolines. J Mass Spectrom. 2011 Oct;46(10):1039-45
(2RS,3RS)-5-amino-3-(4-phenylpiperazin-1-yl)-1,2,3,4-tetrahydronaphthalen-2-ol  0   *Naphthalenes *Piperazines. Acta Crystallogr C. 2011 Oct;67(Pt 10):o378-81
IQ-143 compound  0   *Isoquinolines *Naphthalenes. Genome Biol. 2011;12(3):R24
(1-hexyl-1H-indol-3-yl)-1-naphthalenylmethanone  0   *Indoles *Naphthalenes. J Anal Toxicol. 2011 Sep;35(7):386-93.
1-(2,4-diamino phenylazo)naphthalene  0   *Naphthalenes. J Fluoresc. 2011 Jul;21(4):1485-97
JWH-073  0   *Indoles *Naphthalenes. Anal Chem. 2011 Jun 1;83(11):4228-36
3,4 dihydronaphthalen-1(2H)-one  0   *Naphthalenes. Med Chem. 2011 May 1;7(3):213-23
2,6-disopropylnaphtalene  0   *Naphthalenes Pesticides. Forensic Sci Int. 2011 Jun 15;209(1-3):e23-5
2-hydroxynaphthalene(dodecylo)-6-sulfonamide  0   *Naphthalenes *Sulfonamides. J Phys Chem B. 2011 Jun 30;115(25):8078-87
2,2'-bis(prop-2-ynyloxy)-1,1'-binaphthyl  0   *Naphthalenes. J Sep Sci. 2011 May;34(10):1133-40
naphtho(1,2-b-7,8-b')dipyrroloimidazole  0   *Imidazoles *Naphthalenes. Angew Chem Int Ed Engl. 2011 May 9;50(20):4649-53
N-benzyl-(3-hydoxy-2-naphthalene)  0   *Naphthalenes. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jun;79(1):197-205
GSK 835726  0   *Naphthalenes *Piperidines Histamine H3 Antagonists. Expert Opin Ther Pat 2011 Mar;21(3):425-9
3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphtho(2,3-b)furan-5-carboxylic acid  0   *Furans *Naphthalenes. Zhong Yao Cai. 2010 Jun;33(6):901-3
4-hydroxy-6,7-dimethoxy-8-methyl-2-naphthoic acid  0   *Naphthalenes. J Org Chem. 2011 Jan 21;76(2):601-8
3-phenylmethylene-1H,3H-naphtho-(1,8-c,d)-pyran-1-one  0   *Naphthalenes *Pyrans. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Feb;78(2):559-65
rubasperone C  0   *Naphthalenes *Pyrones. Planta Med. 2010 Nov;76(16):1888-91
rubasperone B  0   *Naphthalenes *Pyrones alpha-Glucosidases/antagonists & inhibitors Monophenol Monooxygenase/antagonists & inhibitors. Planta Med. 2010 Nov;76(16):1888-91
rubasperone A  0   *Naphthalenes *Pyrones alpha-Glucosidases/antagonists & inhibitors Monophenol Monooxygenase/antagonists & inhibitors. Planta Med. 2010 Nov;76(16):1888-91
2-(furan-2-yl)naphthalen-1-ol  0   *Furans *Naphthalenes. Bioorg Med Chem Lett. 2011 Jan 1;21(1):52-7
RO 5066852  0   *Indoleacetic Acids *Naphthalenes Chymases/antagonists & inhibitors. Cardiovasc Res 2011 Jan 1;89(1):244-52
8a-di-1-propyl-octahydronaphthalen-1-(2H)-one  0   *Naphthalenes. J Appl Microbiol. 2010 Dec;109(6):2151-9
2,6-bis(decyloxy)naphthalene  0   *Naphthalenes. J Phys Chem B. 2010 Dec 2;114(47):15483-94
(1,4-dimethoxynaphthalen-2-yl)(2-hydroxyphenyl)methanone  0   *Naphthalenes. J Org Chem. 2010 Dec 17;75(24):8701-4
blue-H compound  0   *Naphthalenes *Thiophenes. J Am Chem Soc. 2010 Nov 17;132(45):15872-4
blue-Br compound  0   *Naphthalenes *Thiophenes. J Am Chem Soc. 2010 Nov 17;132(45):15872-4
Acid Blue 92  0   *Naphthalenes Coloring Agents. Water Sci Technol. 2010;62(11):2491-500
microstegiol  0   *Naphthalenes. J Org Chem. 2010 Dec 3;75(23):8258-70
2-naphthol-3,7-disulphonate  0   *Naphthalenes *Sulfonic Acids. J Phys Chem A. 2010 Oct 7;114(39):10523-30
diphenyl(1-naphthyl)phosphine  0   *Naphthalenes *Phosphines. Inorg Chem. 2010 Oct 4;49(19):8713-23
7,7'-dihydroxy-5,5'-diisopropyl-6,6'-dimethoxy-3,3'-dimethyl-1,1',4,4'-tetraoxo-2,2'-binaphthalene-8,8'-dicarbaldehyde  0   *Naphthalenes. Acta Crystallogr C. 2010 Oct;66(Pt 10):o517-20
tetra((1-hydroxyiminomethylnaphthalen-2-yloxy)methyl)ethene  0   *Aldehydes *Naphthalenes. Spectrochim Acta A Mol Biomol Spectrosc 2010 Oct 15;77(3):643-51
CMB1 complex  0   *Boron Compounds *Naphthalenes. Chem Commun (Camb). 2010 Sep 21;46(35):6512-4
(S)-2-hydroxy-2'-diphenylphosphino-1,1'-binaphthyl  0   *Naphthalenes. Chem Commun (Camb). 2010 Oct 7;46(37):6980-2
3,3'-(4-fluorophenyl)(2)-1,1'-binaphthol phosphate  0   *Hydrocarbons, Fluorinated *Naphthalenes. Molecules. 2010;15(8) (dup#8):5782-96
6-methoxydiphyllin  0   *Naphthalenes *Lignans. Fitoterapia. 2010 Sep;81(6):509-14
tetrahydrojusticidin B  0   *Naphthalenes *Lignans. Fitoterapia. 2010 Sep;81(6):509-14
N-(2-(1-(3-fluorophenyl)-4-oxo-1,3,8-triazaspiro(4.5)decan-8-yl)ethyl)-2-naphthamide  0   *Naphthalenes *Spiro Compounds Phospholipase D/antagonists & inhibitors. J Med Chem 2010 Sep 23;53(18):6706-19
1-pentyl-3-(1-naphthoyl)indole  0   *Indoles *Naphthalenes Ligands Street Drugs Receptor, Cannabinoid, CB1. Pediatr Emerg Care. 2010 Jun;26(6):462-5
2,2,2-trifluoro-N-(1a,2,7,7a-tetrahydronaphtho(2,3-b)oxiren-3-yl)acetamide  0   *Acetamides *Naphthalenes. Acta Crystallogr C. 2010 Sep;66(Pt 9):o475-8
5-(dimethylamino)-N-(4-ethynylphenyl)-1-naphthalenesulfonamide  0   *Naphthalenes *Sulfonamides. Chem Commun (Camb). 2010 May 28;46(20):3538-40
TAK-070  0   *Biphenyl Compounds *Naphthalenes.
5-(5-(ethylperoxy)pentan-2-yl)-6-methyl-3-methylene-2-oxo-2,3,3a,4,7,7a-hexahydrobenzofuran-4-yl 2-(6-methoxynaphthalen-2-yl)propanoate  0   *Naphthalenes *Sesquiterpenes. Breast Cancer Res 2010;12(1):R9
1,8-chalcogen naphthalene  0   *Naphthalenes *Chalcogens. Chemistry. 2010 Jul 5;16(25):7404-21
shuangancistrotectorine E  0   *Isoquinolines *Naphthalenes Alkaloids Drugs, Chinese Herbal. Chemistry. 2010 Apr 12;16(14):4206-16
shuangancistrotectorine D  0   *Isoquinolines *Naphthalenes Alkaloids Drugs, Chinese Herbal. Chemistry. 2010 Apr 12;16(14):4206-16
shuangancistrotectorine C  0   *Isoquinolines *Naphthalenes Alkaloids Drugs, Chinese Herbal. Chemistry. 2010 Apr 12;16(14):4206-16
shuangancistrotectorine B  0   *Isoquinolines *Naphthalenes Alkaloids Drugs, Chinese Herbal. Chemistry. 2010 Apr 12;16(14):4206-16
shuangancistrotectorine A  0   *Isoquinolines *Naphthalenes Alkaloids Drugs, Chinese Herbal. Chemistry. 2010 Apr 12;16(14):4206-16
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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