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2-Naphthylamine

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Definition: A naphthalene derivative with carcinogenic action.  D25-26 qualif   
Pharmacological Action Carcinogens
Other names beta-Naphthylamine; 2-Aminonaphthalene; beta Naphthylamine; 2 Naphthylamine; 2 Aminonaphthalene
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2,2-dimethyl-3-(4-(naphthalen-2-ylamino)phenyl)-3-(1,2,4)triazol-1-yl-propionic acid methyl ester  0   *Triazoles 2-Naphthylamine/*analogs & derivatives. J Med Chem. 2011 Oct 13;54(19):6824-31.
3-(methyl(1,2,3,4-tetrahydro-2-naphthalenyl)amino)-1-indanone  0   *Indans 2-Naphthylamine/*analogs & derivatives. Bioorg Med Chem Lett 2011 Feb 15;21(4):1191-4
1-(4-sulfanatobutyl)-4-(beta-(2-(di-n-butylamino)-6-naphthyl)butadienyl)quinolinium betaine  0   *Quinolinium Compounds 2-Naphthylamine/*analogs & derivatives. Heart Rhythm 2007 Nov;4(11):1441-51
2-naphthylamine 3,6,8-trisulfonic acid  0   *Sulfonic Acids 2-Naphthylamine/*analogs & derivatives. Chemosphere 2009 Jul;76(5):587-84
NCI 83633  0   Leucine/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. RNA 2009 Mar;15(3):483-92
N,N'-bis-(2-pyridinecarboxaldimine)-1,8-diaminonaphthalene  0   2-Naphthylamine/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Jan;71(5):1851-6
elisabethamine  0   *Hydroquinones 2-Naphthylamine/*analogs & derivatives. J Org Chem 2007 Mar 16;72(6):1895-900
1,5-diaminonaphthalene  0   2-Naphthylamine/*analogs & derivatives. J Mass Spectrom 2006 Feb;41(2):191-201
1,8-diaminonaphthalene  0   2-Naphthylamine/*analogs & derivatives. Org Lett 2005 Jun 23;7(13):2607-9
1-(2-aminonaphth-1-yl)-2-naphthol  0   *Naphthols 2-Naphthylamine/*analogs & derivatives. Nucl Med Biol 2004 Jul;31(5):597-603
C,C,C-trifluoro-N-(5-(2-pyridin-2-ylvinyl)naphthalen-2-yl)methanesulfonamide  0   *Sulfonamides 2-Naphthylamine/*analogs & derivatives. J Med Chem 2004 Apr 8;47(8):1893-9
6-chloroacetyl-2-dimethylaminonaphthalene  0   2-Naphthylamine/*analogs & derivatives. Anal Biochem. 2002 Dec 15;311(2):171-8
6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one  0   2-Naphthylamine/*analogs & derivatives. J Med Chem 2003 Feb 13;46(4):584-90
6-hydroxy-2-aminotetralin-2-carboxylic acid  0   *Amino Acids 2-Naphthylamine/*analogs & derivatives. J Med Chem 2000 Apr 6;43(7):1359-66
aladan  0   Alanine/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives Fluorescent Dyes. Science 2002 May 31;296(5573):1700-3
PD 148903  0   2-Naphthylamine/*analogs & derivatives. J Med Chem 2002 Jun 6;45(12):2349-51
2,3-diamino-1,4-dibromonaphthalene  0   2-Naphthylamine/*analogs & derivatives. Anal Sci 2001 Jul;17(7):859-63
Z7760  0   2-Naphthylamine/*analogs & derivatives. Xenobiotica 2000 Oct;30(10):983-91
6-bromoacetyl-2-dimethylaminonaphthalene  0   2-Naphthylamine/*analogs & derivatives. J Biol Chem 1999 Oct 8;274(41):29156-63
succinyl-alanyl-alanyl-asparaginyl-4-methoxy-2-naphthylamide  0   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. Anal Biochem 1999 Sep 10;273(2):278-83
2-(1,1-dicyanopropenyl-2-)-6-dimethylaminonaphthaleney  0   Acrylonitrile/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. Bioorg Med Chem Lett 1998 Jun 16;8(12):1455-60
alanyl-4-methoxy-2-naphthylamide  0   Alanine/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. J Investig Dermatol Symp Proc 1998 Aug;3(2):180-4
ethyl 4-((3-amino-2-naphthyl)aminomethyl)benzoate  0   *Benzoates 2-Naphthylamine/*analogs & derivatives. Biol Pharm Bull 1997 Dec;20912):1229-32
4-((3-amino-2-naphthyl)aminomethyl)benzoic acid  0   *Benzoic Acids 2-Naphthylamine/*analogs & derivatives. Biol Pharm Bull 1997 Dec;20(12):1229-32
2-aminotetralin-2-carboxylic acid  0   *Amino Acids 2-Naphthylamine/*analogs & derivatives. Neuropeptides 1997 Oct;31(5):483-8
N-propyl-N-(6-(2-(3,5-dihydroxyphenyl)ethylamino)hexyl)-5,6-dihydroxy-1,2,3,4-tetrahydro-2-naphthylamine  0   Dopamine/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. Br J Pharmacol 1997 Oct;122(4):682-6
N-propyl-N-(6-(2-(2-oxo-3H-1,3-benzothiazol-6-yl)ethylamino)hexyl)-5,6-dihydroxy-1,2,3,4-tetrahydro-2-naphthylamine dihydrobromide  0   *Thiazoles 2-Naphthylamine/*analogs & derivatives. Br J Pharmacol 1997 Oct;122(4):682-6
RPR 114334  0   *Dipeptides 2-Naphthylamine/*analogs & derivatives. J Med Chem 1997 Jun 6;40(12):1763-7
glycyl-arginyl-4-methoxy-beta-naphthylamide  0   *Dipeptides 2-Naphthylamine/*analogs & derivatives. Appl Environ Microbiol 1997 Feb;63(2):670-5
patman  0   *Palmitic Acids 2-Naphthylamine/*analogs & derivatives. Biophys Chem 1996 Oct 30;61(2-3):151-60
N,N-di-n-propyl-5,6,7,8-tetrahydro-1H-benz(f)benzimidazol-6-ylamine  0   *Benzimidazoles 2-Naphthylamine/*analogs & derivatives. Pharmazie 1995 Oct;50(10):678-80
di-2-naphthylurea  0   Urea/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. Environ Health Perspect 1994 Oct;102 Suppl 6:115-8
7-(N,N-dipropylamino)-5,6,7,8-tetrahydronaphtho(2,3-b)dihydro-2,3-furan  157622-55-4 Naphtho(2,3b)furan-7-amine, 2,3,5,6,7,8-hexahydro-N,N-dipropyl-, (+)  *Furans 2-Naphthylamine/*analogs & derivatives Ligands. Eur J Pharmacol 1994 Aug 1;260(2-3):R3-5
N-hydroxy-2-naphthylamine DNA adduct  0   *DNA Adducts 2-Naphthylamine/*analogs & derivatives. Anal Biochem 1994 May 15;219(1):121-30
prolyl-beta-naphthylamide  16037-15-3   Proline/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. Biol Chem Hoppe Seyler 1993 Nov;374(11):1033-6
glutaryl-alanyl-alanyl-phenylalanyl-4-methoxy-2-naphthylamine  0   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. Exp Physiol 1993 Jan;78(1):35-48
lysine-2-naphthylamide  4420-88-6   Lysine/*analogs & derivatives 2-Naphthylamine/*analogs & derivatives. J Biochem Toxicol 1992 Fall;7(3):171-5
succinyl-phenylalanyl-leucyl-phenylalanine-4-methoxynaphthylamide  129219-63-2   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. Biochem Soc Trans 1990;18(4):589
laurdan  74515-25-6   *Laurates 2-Naphthylamine/*analogs & derivatives.
Pharma Action Fluorescent Dyes
Biophys J 1990;57(6):1179
succinyl-alanyl-alanyl-phenylalanyl-4-methoxy-2-naphthylamide  85613-77-0   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. J Histochem Cytochem 1989;37(4):415
benzyloxycarbonyl-alanyl-alanyl-lysyl-4-methoxy-2-naphthylamide  63244-88-2   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. J Histochem Cytochem 1989;37(4):415
benzyloxycarbonyl-arginyl-glycyl-phenylalanyl-phenylalanyl-leucine-4-methoxy-2-naphthylamine  0   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. Histochemistry 1988;88(3-6):505
benzyloxycarbonyl-arginyl--glycyl-phenylalanyl-phenylalanyl-proline-4-methoxy-2-naphthylamine  0   *Oligopeptides 2-Naphthylamine/*analogs & derivatives. Histochemistry 1988;88(3-6):505
prodan-phosphatidylcholine  0   *Phosphatidylcholines 2-Naphthylamine/*analogs & derivatives. Biochemistry 1987;26(12):3697
black rubber  0   *Phenylenediamines 2-Naphthylamine/*analogs & derivatives Allergens Dermatitis, Contact/etiology. Contact Dermatitis 1987;17(1):42
2-amino-5-(bis(2-chloroethyl)amino)-1,2,3,4-tetrahydro-2-naphthoic acid  106114-32-3   *Nitrogen Mustard Compounds 2-Naphthylamine/*analogs & derivatives. J Med Chem 1987;30(3):542
2-amino-7-(bis(2-chloroethyl)amino)-1,2,3,4-tetrahydro-2-naphthoic acid  106094-83-1   *Nitrogen Mustard Compounds 2-Naphthylamine/*analogs & derivatives. J Med Chem 1987;30(3):542
SK&F 88444  67707-80-6   2-Naphthylamine/*analogs & derivatives. J Pharmacol Exp Ther 1986;238(1):89
8-methoxy-2-(N-2'-chloropropyl-N-propyl)aminotetralin  96426-45-8 2-Naphthalenamine, N-(2-chloropropyl)-1,2,3,4-tetrahydro-8-methoxy-N-propyl-, (R)  2-Naphthylamine/*analogs & derivatives. Biochem Pharmacol 1985;34(6):883
acrylodan  86636-92-2 2-Propen-1-one, 1-(6-(dimethylamino)-2-naphthalenyl)  2-Naphthylamine/*analogs & derivatives.
Pharma Action Fluorescent Dyes
J Biol Chem 1983;258(120:7541
prodan  70504-01-7 1-Propanone, 1-(6-(dimethylamino)-2-naphthalenyl)  2-Naphthylamine/*analogs & derivatives.
Pharma Action Fluorescent Dyes
J Biol Chem 1983;258(12):7541
2-amino-1,2-dihydronaphthalene  81094-65-7 2-Naphthalenamine, 1,2-dihydro-, (+-)  2-Naphthylamine/*analogs & derivatives. J Med Chem 1981;25(5):535
amido-G-acid  86-65-7   2-Naphthylamine/*analogs & derivatives. JNCI 1981;67(6):1299
badische acid  86-60-2   2-Naphthylamine/*analogs & derivatives. JNCI 1981;67(6):1299
2-amino-5,8-dimethoxy-6-methyl-1,2-dihydronaphthalene  80387-95-7 2-Naphthalenamine, 1,2-dihydro-5,8-dimethoxy-6-methyl  2-Naphthylamine/*analogs & derivatives. J Med Chem 1981;24(7):882
N-hydroxy-2-naphthylamine-N-glucuronide  62317-15-1   2-Naphthylamine/*analogs & derivatives. Chem Biol Interact 1981;33(2-3):129
2,3-diaminonaphthalene  771-97-1   2-Naphthylamine/*analogs & derivatives. Clin Chem 1980;26(9):1272
N-(3-hydroxy-1,2,3,4-tetrahydro-2-naphthyl)-N-(3-oxo-3-phenyl-2-methylpropyl)piperazine  58170-82-4 (trans)-2-methyl-1-phenyl-3-(4-(1,2,3,4-tetrahydro-3-hydroxy-2-naphthalenyl)-1-piperazinyl)-1-propanone  2-Naphthylamine/*analogs & derivatives. Acta Physiol Pharmacol Bulg 1979;5(3):51
6-propionyl-2-(dimethylamino)naphthalene  0   2-Naphthylamine/*analogs & derivatives. Biochemistry 18(14):3075;1979
N-hydroxy-2-naphthylamine  613-47-8   2-Naphthylamine/*analogs & derivatives. Biochem Pharmacol 28(5):695;1979
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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