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Thiazoles

More information in Books or onNLM PubMed
Definition:   includes thiazolines, thiazolidines   
Examples Chlormethiazole; Dithiazanine; Ethoxzolamide; Famotidine; FANFT; Firefly Luciferin; Levamisole; Niridazole; Nizatidine; Oxythiamine; Rhodanine; Riluzole; Ritonavir; Saccharin; Sulfathiazoles; Tetramisole; Thiabendazole; Thiadiazoles; Thiamine; Thiazolidinediones; Thiazolidines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
fluensulfone  0   *Sulfones *Thiazoles. Pest Manag Sci. 2012 Feb;68(2):268-75.
4,5-dichloro-1,2,3-dithiazolium chloride  0   *Thiazoles. Molecules. 2011;16(11) (dup#20):8992-9002
2-acetoxybenzoyl-N-(5-chlorothiazol-2-yl)amide  0   *Thiazoles. J Med Chem. 2011 Dec 22;54(24):8670-80.
3-((5-((1,2,4)triazolo(1,5-a)pyridin-6-yl)-4-(6-methylpyridin-2-yl)thiazol-2-ylamino)methyl)benzonitrile  0   *Pyridines *Thiazoles. Cancer Sci. 2011 Oct;102(10):1889-96.
(2-(2,6-dichlorobenzyl)thiazolo(5,4-d)pyrimidin-7-yl)-(4-trifluoromethylphenyl)amine  0   *Pyrimidines *Thiazoles TRPV Cation Channels/antagonists & inhibitors. Eur J Pharmacol 2011 Aug 1;663(1-3):40-50
des-methyl, des-amino pateamine A  0   *Epoxy Compounds *Thiazoles *Macrolides. Mol Cancer Ther. 2009 May;8(5):1250-60
N-(2-5-chloro-2-methoxyphenylamino)4'-methyl(4,5''bithiazolyl-2'-yl)benzamide  0   *Benzamides *Thiazoles. Am J Physiol Lung Cell Mol Physiol. 2011 Sep;301(3:L346-52
6-(4-chlorophenyl)-4-methyl-6H-pyrazolo(3,4-c)isothiazol-3-amine  0   *Pyrazoles *Thiazoles. Drug Chem Toxicol 2011 Jul;34(3):324-31
N-(4-(2-(2-propylpyridin-4-yl)thiazol-4-yl)phenyl)methanesulfonamide  0   *Sulfonamides *Thiazoles. J Med Chem 2011 Jul 14;54(13):4923-7
2-hydroxybenzoyl-N-(5-chlorothiazol-2-yl)amide  0   *Salicylamides *Thiazoles. J Med Chem 2011 Jun 23;54(12):4119-32
benzo(d)thiazol-2-amine  0   *Thiazoles. Inorg Chem. 2011 Jun 6;50(11):4732-41
9-((3-chloro)phenylamine)-2-(3-(diethylamine)propylamine)thiazolo(5,4-b)quinoline  0   *Aminoquinolines *Thiazoles. Eur J Med Chem 2011 Jun;46(6):2102-8
lyngbyabellin C  0   *Lyngbya Toxins *Thiazoles. ACS Chem Biol 2011 May 20;6(5):425-31
2-isopropyl-4-methyl-3-thiazoline  0   *Thiazoles. J Food Sci. 2011 Apr;76(3):C385-91
2-ethyl-4-methyl-3-thiazoline  0   *Thiazoles. J Food Sci. 2011 Apr;76(3):C385-91
4-fluoro-N-(4-(6-(isopropylamino)pyrimidin-4-yl)-1,3-thiazol-2-yl)-N-methylbenzamide  0   *Benzamides *Thiazoles Fluorine Radioisotopes. Bioorg Med Chem Lett 2011 May 15;21(10):2998-3001
2-(3,4-dimethoxybenzenesulfonylamino)-4-(3-nitrophenyl)-5-(piperidin-1-yl)methylthiazole  0   *Sulfonamides *Thiazoles. Cell 2011 Jun 10;145(6):863-74
archazolid A-15-O-beta-D-glucopyranoside  0   *Glucosides *Thiazoles *Macrolides. J Nat Prod. 2011 May 27;74(5):1100-5
DEAB-TO-3 compound  0   *Quinolines *Thiazoles Fluorescent Dyes. Angew Chem Int Ed Engl. 2011 Apr 26;50(18):4180-3
7-(3-(2-aminopropan-2-yl)pyrrolidin-1-yl)-9-cyclopropyl-6-fluoro-8-methoxyisothiazolo(5,4-b)quinoline-3,4(2H,9H)-dione  0   *Thiazoles *Quinolones. J Med Chem 2011 May 12;54(9):3268-82
7-(3-(1-aminoethyl)pyrrolidin-1-yl)-9-cyclopropyl-6-fluoro-8-methoxyisothiazolo(5,4-b)quinoline-3,4(2H,9H)-dione  0   *Thiazoles *Quinolones. J Med Chem 2011 May 12;54(9):3268-82
phosphoric acid mono-(2-(4-(3,3-dimethylbutyrylamino)-3,5-difluorobenzoylimino)thiazol-3-ylmethyl) ester  0   *Phosphoric Acid Esters *Thiazoles. J Pharm Biomed Anal 2011 Jun 1;5(3):424-8
N-(5-(2-bromobenzyl)thiazole-2-yl)benzofuran-2-carboxamide  0   *Benzofurans *Thiazoles. Cancer Lett 2011 Jul 28;306(2):190-6
AZ 876  0   *Aniline Compounds *Thiazoles Orphan Nuclear Receptors/agonists. Br J Pharmacol 2011 Apr;162(7):1553-63
2-(5-(3-phenoxybenzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid  0   *Benzylidene Compounds *Thiazoles. Bioorg Med Chem. 2010 Jul 1;18(13):4630-8
cobicistat  0   *Carbamates *Thiazoles. Clin Pharmacol Ther 2010 Mar;87(3):322-9
spoxazomicin B  0   *Oxazoles *Thiazoles. J Antibiot (Tokyo). 2011 Apr;64(4):303-7
spoxazomicin A  0   *Oxazoles *Thiazoles. J Antibiot (Tokyo). 2011 Apr;64(4):303-7
SR1001  0   *Sulfonamides *Thiazoles. Nature. 2011 Apr 28;472(7344):491-4
2-(4-chlorophenyl)-5-(4-methoxybenzylidene)-5H-thiazol-4-one  0   *Benzylidene Compounds *Thiazoles Lipoxygenase Inhibitors. J Med Chem 2011 Mar 24;54(6):1943-7
3-bromoisothiazole-4-carbonitrile  0   *Nitriles *Thiazoles. Org Lett. 2011 Mar 18;13(6):1510-3
5-carboxymeloxicam  0   *Thiazines *Thiazoles. Bioanalysis. 2009 Apr;1(1):63-70
6-chloro-N-(3-(2-(dimethylamino)ethyl)-1H-indol-5-yl)imidazo(2,1-b)thiazole-5-sulfonamide  0   *Indoles *Sulfonamides *Thiazoles. Psychopharmacology (Berl). 2011 Feb;213(2-3):413-30
2-(3-chloro-4-fluorophenyl)isothiazol-3-one  0   *Thiazoles Peptidylprolyl Isomerase/antagonists & inhibitors Cyclophilins/antagonists & inhibitors. Biochem Biophys Res Commun 2011 Mar 18;406(3):439-43
N-((1-((5-(4-fluorophenyl)-2-methyl-4-thiazolyl)carbonyl)-2-piperidinyl)methyl)-4-benzofurancarboxamide  0   *Benzofurans *Thiazoles Carbon Radioisotopes. Drug Metab Dispos 2011 Feb;39(2):215-27
N,N'-di(p-thiazole)formamidine  0   *Formamides *Thiazoles. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Jan;78(1):88-95
3-acetyl-6-chloro-2-(2-(3-(N-(2-ethoxyethyl)-N-isopropylamino)propoxy)-5-methoxyphenyl)benzothiazoline O,O'-diacetyl-L-tartrate  0   *Tartrates *Thiazoles. Eur J Pharmacol. 2010 Nov 25;647(1-3):62-7
(((5-(1,1-dimethylethyl)thiazol-2-yl)methyl)(((4-(4-(4-(1-propylbutyl)phenoxy)methyl)phenyl)thiazol-2-yl)methyl)amino)acetic acid  0   *Thiazoles Glycine/*analogs & derivatives Protein Tyrosine Phosphatase, Non-Receptor Type 1/antagonists & inhibitors. Diabetes Obes Metab 2010 Apr;12(4):299-306
4,5-dihydro-1,3,2-dithiazolyl  0   *Thiazoles. Magn Reson Chem. 2010 Dec;48 Suppl 1():S122-31
4-(3,4,5-trimethoxybenzoyl)-2-phenylthiazole  0   *Thiazoles. Drug Metab Dispos 2010 Nov;38(11):2032-9
FB2 compound  0   *Pyrimidines *Thiazoles. Leuk Res. 2011 Feb;35(2):237-42
2-((4-fluoro-3-(trifluoromethyl)phenyl)amino)-4-(4-pyridinyl)-5-thiazolemethanol  0   *Pyridines *Thiazoles. J Pharmacol Exp Ther 2011 Feb;336(2):560-74
3-methylthio-5-phenyl-4-isothiazolecarbonitrile  0   *Nitriles *Thiazoles Poliovirus. Antiviral Res. 2010 Dec;88(3):325-8
2,2'-(5,5'-(9,9-didecyl-9H-fluorene-2,7-diyl)bis(ethyne-2,1-diyl)bis(thiophene-5,2-diyl))dibenzo(d)thiazole  0   *Thiazoles *Thiophenes. J Phys Chem B. 2010 Nov 11;114(44):14087-95
TP 1161  0   *Peptides, Cyclic *Thiazoles. Appl Environ Microbiol 2010 Nov;76(21):7093-101
N-(3-methyl-5-isothiazolyl)-2-1-((3-methyl-5-isoxazolyl)methyl)-1H-3-indolyl-2-oxoacetamide  0   *Indoles *Thiazoles. Cancer Sci 2011 Jan;102(1):182-91
3-(4-iodophenyl)-2-(4-(3,4-dichlorophenyl)thiazol-2-ylamino)propionic acid  0   *Thiazoles Phenylalanine/*analogs & derivatives. Int J Antimicrob Agents 2010 Oct;36(4):364-8
3-amino-6-(4-chloro-2-hydroxy-5-methylphenyl)-1H-pyrazolo(3,4-d)thiazolo(3,2-a)pyrimidin-4-one  0   *Pyrimidinones *Thiazoles Xanthine Oxidase/antagonists & inhibitors. J Enzyme Inhib Med Chem 2010 Oct;25(5):615-21
3-amino-6-(2-hydroxyphenyl)-1H-pyrazolo(3,4-d)thiazolo(3,2-a)pyrimidin-4-one  0   *Pyrimidinones *Thiazoles Xanthine Oxidase/antagonists & inhibitors. J Enzyme Inhib Med Chem 2010 Oct;25(5):615-21
4-(4-(4-fluorophenyl)thiazol-2-ylamino)-2,6-dimethylphenol  0   *Thiazoles *Xylenes. Pharmacology 2010;86(2):65-72
tyrosine phosphatase inhibitor-3  0   *Thiazoles Protein Tyrosine Phosphatases/antagonists & inhibitors. Mol Cancer Ther 2010 Aug;9(8):2287-96
KNI 10742  0   *Ethylenediamines *Thiazoles. Bioorg Med Chem Lett 2010 Aug 15;20(16):4836-9
KNI 10743  0   *Ethylenediamines *Thiazoles. Bioorg Med Chem Lett 2010 Aug 15;20(16):4836-9
2-(1-thieno(3,2-d)pyrimidin-4-ylpiperidin-4-yl)thiazole-4-carboxylic acid (6-benzoyl-1H-benzoimidazol-2-yl)amide  0   *Benzimidazoles *Thiazoles. Mol Cancer Ther 2010 Feb;9(2):300-10
(5-(2-amino-5-(2-methylpropyl)-4-thiazolyl)-2-furanyl)phosphonic acid  0   *Phosphonic Acids *Thiazoles Fructose-Bisphosphatase/antagonists & inhibitors. Proc Natl Acad Sci U S A 2005 May 31;102(22):7970-5
KHS101  0   *Thiazoles Neurogenesis/drug effects. Proc Natl Acad Sci U S A. 2010 Sep 21;107(38):16542-7
aeruginazole A  0   *Peptides, Cyclic *Thiazoles Bacillus subtilis/drug effects. Org Lett. 2010 Aug 6;12(15):3536-9
2-amino-4-acetylthiazolo(5,4-b)indole hydrobromide  0   *Indoles *Thiazoles. Eksp Klin Farmakol. 2010 Jul;73(7):19-22
N6-(2-(4-(biphenyl-4-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo(d)thiazole-2,6-diamine  0   *Biphenyl Compounds *Piperazines *Thiazoles Receptors, Dopamine D3/agonists. J Neurosci Res. 2010 Aug 15;88(11):2513-23
3,3'-(4,4'-(1,4-phenylene)bis(butane-4,1-diyl))bis(5-(2-methoxyethyl)-4-methylthiazol-3-ium)  0   *Thiazoles. ChemMedChem 2010 Jul 5;5(7):1102-91102-9
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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