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Pyridines

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Definition: Compounds with a six membered aromatic ring containing NITROGEN. The saturated version is PIPERIDINES.  pyridine nucleotides will probably be NAD or NADP   
See Also Piperidines
Examples 2-Pyridinylmethylsulfinylbenzimidazoles; Aminopyridines; Betahistine; Carbolines; Clopidol; Dihydropyridines; Dimethindene; 2,2'-Dipyridyl; Disopyramide; Doxylamine; Indinavir; Isonicotinic Acids; 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Metyrapone; Naphthylvinylpyridine; Nevirapine; Nicotine; Nicotinic Acids; Nicotinyl Alcohol; Pheniramine; Picolines; Picolinic Acids; Polyvinylpyridine N-Oxide; Pyridinium Compounds; Pyridones; Pyrithioxin; Quinolinic Acids; Thienopyridines; Tolperisone; Triprolidine; Tropicamide
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)-3,3-dimethyl-2-((4-pyridinylmethyl)amino)-1-butanone  0   *Isoquinolines *Pyridines. J Pharmacol Exp Ther. 2010 Aug;334(2):522-9.
HS-104  0   *Imidazoles *Pyridines Phosphatidylinositol 3-Kinase/antagonists & inhibitors. Cancer Lett. 2012 May 1;318(1):68-75
MK-1597  0   *Cyclopropanes *Pyridines. J Org Chem. 2011 Feb 18;76(4):1062-71
2'-aminoethoxy-2-amino-3-methylpyridine  0   *Pyridines. Chemistry. 2011 Dec 23;17(52):14718-22
monapurpyridine A  0   *Pyridines. Molecules. 2012;17(1) (dup#13):664-73
pyridine-2,6-dicarboxamide  0   *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb;86():614-24
4-(2-pyridylazo)-N,N-diethylaniline  0   *Aniline Compounds *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb;86():538-46
4-(2-pyridylazo)-N,N-dimethylaniline  0   *Aniline Compounds *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2012 Feb;86():538-46
4-(6-methoxy-2-naphthyl)-2-(4-methylsulfinylphenyl)-5-(4-pyridyl)-1H-imidazole  0   *Imidazoles *Pyridines. Neoplasia. 2012 Feb;14(2):131-40.
VU0448383  0   *Pyridines. Bioorg Med Chem Lett. 2011 Dec 1;21(23):6955-9
coprismycin A  0   *Oximes *Pyridines. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5715-8.
1-(5-chloropyridin-3-yl)-(1,4)diazepane  0   *Azepines *Pyridines Nicotinic Agonists. J Psychopharmacol. 2011 Oct;25(10):1347-56.
MK-3328  0   *Oxazoles *Pyridines. Nucl Med Biol. 2011 Nov;38(8):1193-203.
3-(2-azetidinylmethoxy)-5-(3'-fluoropropyl)pyridine  0   *Azetidines *Pyridines Fluorine Radioisotopes Nicotinic Antagonists. Nucl Med Biol. 2011 Nov;38(8):1183-92.
2,6-bis(bis(2-pyridylmethyl)aminomethyl)-4-methylphenol  0   *Phenols *Pyridines. Chemistry. 2011 Nov 25;17(48):13482-94
E-1 styrylpyridine-crown ether  0   *Pyridines *Crown Ethers. Photochem Photobiol Sci. 2011 Dec;10(12):1954-62
2-ethyl-6-methylpyridin-3-ol  0   *Pyridines. Acta Crystallogr C. 2012 Jan;68(Pt 1):o33-6
P3155  0   *Pyridines *Pyrimidines Hypoxia-Inducible Factor 1, alpha Subunit/antagonists & inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6426-9.
2,6-bis(4-diphenylaminostyrylcarbonyl)pyridine  0   *Pyridines Diphenylamine/*analogs & derivatives. Analyst. 2011 Dec 21;136(24):5283-6.
5-((R)-1-hydroxyethyl)-furo(2,3-c)pyridine  0   *Pyridines. Biosci Biotechnol Biochem. 2011;75(11):2155-61
5-acetylfuro(2,3-c)pyridine  0   *Pyridines. Biosci Biotechnol Biochem. 2011;75(11):2155-61
2-(2'-(biphenyl-3-ylmethylcarbamoyl)-6,6'-bis(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-4,4'-bipyridine-2-carboxamido)-2-cyclohexylacetic acid  0   *Pyridines *Pyrrolidines CD40 Ligand/antagonists & inhibitors. ACS Chem Biol. 2011 Jun 17;6(6):636-47.
(2S)-N,N'-(disulfanediyldiethane-2,1-diyl)bis(4-(2-pyridin-3-ylpyrrolidin-1-yl)butanamide)  0   *Pyridines *Pyrrolidines. Biochem Pharmacol. 2012 Feb 15;83(4):543-50
4'-(4-(4,5-diphenyl-1H-imidazol-2-yl)phenyl)-(2,2'-6',2'')terpyridine  0   *Imidazoles *Pyridines Ligands. Dalton Trans. 2011 Nov 28;40(44):11795-808.
2-(2-fluoroethoxy)-1,3-di(2-(2-(2-(5-(4-(methylamino)styryl)pyridin-2-yloxy)ethoxy)ethoxy)ethoxy)propane  0   *Pyridines *Styrenes. J Med Chem. 2011 Dec 8;54(23):8085-98.
KX2 329  0   *Acetamides *Pyridines src-Family Kinases/antagonists & inhibitors. Neurosci Res. 2011 Dec;71(4):348-54.
5,7-dihydroxy-8-(pyridine-4-yl)flavone  0   *Pyridines *Flavones. Eur J Pharmacol. 2011 Nov 30;670(2-3):617-22.
bis(2-hydroxypyridine)dichloroplatinum(II)  0   *Organoplatinum Compounds *Pyridines. Anticancer Res. 2012 Jan;32(1):135-40.
1-(2-pyridyl)-2-propen-1-ol  0   *Pyridines *Propanols. J Org Chem. 2011 Nov 18;76(22):9536-41
6-(2-pyridinyl)-5,6-dihydrobenzimidazo(1,2-c)quinazoline  0   *Pyridines *Quinazolines. Analyst. 2011 Nov 21;136(22):4839-45
2,6-pyridinedimethanol  0   *Pyridines Methanol/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Dec 15;84(1):168-77
2,6-bis(5,6-dipropyl-1,2,4-triazin-3-yl)pyridine  0   *Pyridines *Triazines. J Hazard Mater. 2011 Nov 15;195():238-44
bis(4'-(9-anthryl)-2,2':6',2''-terpyridine)copper(II)  0   *Pyridines *Coordination Complexes Copper. Dalton Trans. 2011 Nov 7;40(41):10865-72.
8-methoxy-2,3,4,4a,5,9b-hexahydro-1H-pyrido(4,3-b)indolinium  0   *Indoles *Pyridines. Pharmacol Rep. 2011;63(4):967-74.
3-(4-pyridyl)-1H-indole  0   *Indoles *Pyridines rho-Associated Kinases/antagonists & inhibitors. Development. 2012 Jan;139(2):437-42
3-(2-(5-(2-pyridin-4-ylvinyl)pyridin-3-yl)vinyl)aniline  0   *Aniline Compounds *Pyridines. Eur J Pharmacol. 2011 Nov 1;669(1-3):7-14.
S35972  0   *Pyrazines *Pyridines *Pyrroles Anticoagulants. J Thromb Haemost. 2011 Jul;9(7):1375-82
4-(1-((5-((2,6-dimethylphenoxy)methyl)-3-isoxazolyl)carbonyl)-4-piperidinyl)pyridine  0   *Isoxazoles *Piperidines *Pyridines. Nat Chem Biol. 2011 Dec;7(12):891-3
2-(2'-hydroxyphenyl)-4-methylimidazo(4,5-b)pyridine  0   *Imidazoles *Pyridines. Photochem Photobiol Sci. 2011 Oct;10(10):1622-36.
2-(2'-methoxyphenyl)imidazo(4,5-b)pyridine  0   *Imidazoles *Pyridines. Photochem Photobiol Sci. 2011 Oct;10(10):1622-36.
3-((5-((1,2,4)triazolo(1,5-a)pyridin-6-yl)-4-(6-methylpyridin-2-yl)thiazol-2-ylamino)methyl)benzonitrile  0   *Pyridines *Thiazoles. Cancer Sci. 2011 Oct;102(10):1889-96.
2-chloro-4-((2,5-dimethyl-1-(4-(trifluoromethoxy)phenyl)-1H-imidazol-4-yl)ethynyl)pyridine  0   *Imidazoles *Pyridines. J Pharmacol Exp Ther. 2011 Nov;339(2):474-86.
polystyrene-block-poly(2-vinylpyridine)  0   *Polystyrenes *Polyvinyls *Pyridines. Langmuir. 2011 Oct 4;27(19):12191-6
N-undecyl-N'-(2-methylpyrene)-N''(2-methylpyridine)amine  0   *Pyrenes *Pyridines. Chemistry. 2011 Sep 12;17(38):10574-82
3-amino-N-(4-chlorobenzyl)-6-(3-methoxyphenyl)thieno(2,3-b)pyridine-2-carboxamide  0   *Pyridines *Thiophenes. Cancer Lett. 2011 Dec 26;313(1):44-53.
2-(2-methyl-4-((1-(6-(4-(trifluoromethyl)phenyl)-2-pyridinyl)pentyl)oxy)phenoxy)acetic acid  0   *Acetic Acids *Pyridines PPAR delta/agonists. Diabetes Obes Metab. 2011 May;13(5):455-64.
(Z)-3-(2-methyl-1-butenyl)pyridine  0   *Pyridines. J Nat Prod. 2011 Oct 28;74(10):2231-4
3-((4-((1,2,4)triazolo(1,5-a)pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1H-imidazol-2-yl)methylamino)benzonitrile  0   *Pyridines *Triazoles. Eur J Cancer. 2011 Nov;47(17):2642-53.
(2R)-2-(3-(3,5-bis(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)- pyridine-1(4H)-3-oxoacetyl)amino)-4-(methylthio)butanoic Acid  0   *Butyric Acids *Pyridines. Chem Pharm Bull (Tokyo). 2011;59(9):1153-6
(2S)-2-(3-(3,5-bis(methoxycarbonyl)-2,6-dimethyl-4-(2-nitrophenyl)- pyridine-1(4H)-3-oxoacetyl)amino)-3-phenylpropanoic Acid  0   *Phenylpropionates *Pyridines. Chem Pharm Bull (Tokyo). 2011;59(9):1153-6
5-(3,6-diazabicyclo(3.2.0)heptan-6-yl)nicotinonitrile  0   *Pyridines *Azabicyclo Compounds. Biochem Pharmacol. 2007 Oct 15;74(8):1253-62.
texaline  0   *Oxazoles *Pyridines Antitubercular Agents. Chemistry. 2011 Aug 29;17(36):10113-22
2-(2-chlorophenyl)-3-(cyclohexylamino)imidazo(1,2-a)pyridine-5-carbonitrile  0   *Imidazoles *Pyridines. Bioorg Med Chem. 2011 Jul 15;19(14):4227-37.
BTZO-15 compound  0   *Pyridines *Thiazines. PLoS One. 2011;6(8):e23256.
3-(4-((2,6-dichloropyridin-4-yl)ethynyl)phenyl)propanoic acid  0   *Phenylpropionates *Pyridines. J Med Chem. 2011 Oct 13;54(19):6691-703.
2,6-bisamidopyridine  0   *Pyridines. J Org Chem. 2011 Aug 19;76(16):6780-8
2,6-bis(4'-nitrenophenyl)-4-phenylpyridine  0   *Pyridines. J Phys Chem A. 2011 Aug 4;115(30):8419-25
2-bromo-3-pyridinecarboxaldehyde  0   *Aldehydes *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1559-65
2-chloro-3-pyridinecarboxaldehyde  0   *Aldehydes *Pyridines. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Sep;79(5):1559-65
2,4,6-tri-tert-butylpyridine  0   *Pyridines. Org Lett. 2011 Sep 16;13(18):4854-7
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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