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Triazines

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Definition: Heterocyclic rings containing three nitrogen atoms, commonly in 1,2,4 or 1,3,5 or 2,4,6 formats. Some are used as HERBICIDES.  do not confuse with TRIAZENES   
Examples Almitrine; Altretamine; Apazone; Atrazine; Ferrozine; Oxonic Acid; Prometryne; Simazine; Triethylenemelamine 		Other names Benzotriazines
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
1,6-dimethyl-3-propylpyrimido(5,4-e)(1,2,4)triazine-5,7-dione  0   *Pyrimidinones *Triazines. Mol Pharm. 2011 Dec 5;8(6):2252-61.
melem  0   *Heterocyclic Compounds, 3-Ring *Triazines. Chemistry. 2012 Mar 12;18(11):3248-57
CH5015765  0   *Benzopyrans *Triazines. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5778-83.
5-ethyl-5-(piperidin-1-yl)-1,3-diazinane-2,4,6-trione  0   *Piperidines *Triazines. Acta Crystallogr C. 2012 Feb;68(Pt 2):o65-70
N-(2,3-dihydro-2,6-dimethyl-1H-inden-1-yl)-6-(1-fluoroethyl)-1,3,5-triazine-2,4-diamine  0   *Indenes *Triazines. Bull Environ Contam Toxicol. 2012 Mar;88(3):326-32.
BMS-813160  0   *Triazines Pyrazoles Cardiovascular Agents. Expert Opin Ther Pat. 2011 Dec;21(12):1919-24
CEN-209  0   *Cyclic N-Oxides *Triazines. Biochem Pharmacol. 2012 Mar 1;83(5):574-85.
2,4-diaminotriazine  0   *Triazines. Langmuir. 2011 Nov 1;27(21):12851-8
2,6-bis(5,6-dipropyl-1,2,4-triazin-3-yl)pyridine  0   *Pyridines *Triazines. J Hazard Mater. 2011 Nov 15;195():238-44
2,4-bis(4'-fluorophenethylamino)-6-(3'-(N,N-dimethylamino)propylamino)-1,3,5-triazine  0   *Triazines. J Med Chem. 2011 Nov 10;54(21):7441-52.
Reactive Red M-2BE  23354-52-1   *Naphthalenesulfonates *Triazines Coloring Agents. J Hazard Mater. 2011 Sep 15;192(3):1122-31
N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)-4-((4-((2-(2-(2-benzamidoethoxy)ethoxy)ethyl)amino)-6-((4-hydroxyphenyl)amino)-1,3,5-triazin-2-yl)amino)benzamide  0   *Triazines 4-Aminobenzoic Acid/*analogs & derivatives. J Pharmacol Exp Ther. 2011 Nov;339(2):633-41.
OSI 027  0   *Imidazoles *Triazines. Mol Cancer Ther. 2011 Aug;10(8):1394-406.
N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide  0   *Acetamides *Triazines. J Med Chem 2011 Jul 14;54(13):4427-45
PAF-6 compound  0   *Triazines Polymers. Chem Commun (Camb). 2011 Jun 14;47(22):6389-91
N6-(3-(4-chlorophenoxy)propyl)-2-(furan-2-yl)-1,2-dihydro-1,3,5-triazine-4,6-diamine  0   *Triazines. Eur J Med Chem 2011 Jun;46(6):2022-30
2,4,6-tris(thiophen-2-yl)-1,3,5-triazine  0   *Thiophenes *Triazines. Phys Chem Chem Phys. 2011 May 21;13(19):8838-46
N-(4-fluorobenzoyl)-N'-(2-(5-(4-fluorobenzyl)-1-(4-methoxybenzyl)-4,6-dioxo-1,4,5,6-tetrahydro(1,3,5)triazin-2-ylamino)ethyl)guanidine  0   *Guanidines *Triazines Fluorine Radioisotopes. J Nucl Med 2011 Apr;52(4):600-7
2-(2-ethoxy-5-(2-(4-ethylpiperazin-1-yl)acetyl)phenyl)-5-methyl-7-propyl-imidazo(5,1-f)-(1,2,4)triazin-4(3H)-one  0   *Imidazoles *Piperazines *Triazines. J Pharm Biomed Anal. 2011 Feb 20;54(3):491-6
remazol red brilliant  0   *Naphthalenesulfonates *Triazines. Water Sci Technol. 2011;63(4):613-7
trichloroisocyanuric acid  0   *Triazines. J Org Chem. 2011 Jan 7;76(1):277-80
N,N',N''-trihydroxyisocyanuric acid  0   *Triazines. J Hazard Mater 2010 Dec 15;184(1-3):400-5
2-methoxy-4-ethylamino-6-ethylamino-1,3,5-triazine  0   *Triazines. Environ Monit Assess 2010 Nov;170(1-4):59-63
3-(2-methoxybenzyloxycarbonyl)-8-trifluoromethylpyrazolo(5,1-c)(1,2,4)benzotriazine 5-oxide  0   *Pyrazoles *Triazines. J Med Chem 2010 Nov 11;53(21):7532-48
benzotriazine-2-thione  0   *Thiones *Triazines. Nucleosides Nucleotides Nucleic Acids 2010 Sep;29(9):698-706
CE-178253  0   *Azetidines *Triazines. BMC Pharmacol. 2010;10() (dup#11): 9
1-(7-(2-chlorophenyl)-8-(4-chlorophenyl)-2-methylpyrazolo(1,5-a)(1,3,5)triazin-4-yl)-3-(methylamino)azetidine-3-carboxamide  0   *Azetidines *Triazines Receptor, Cannabinoid, CB1/antagonists & inhibitors. J Pharmacol Exp Ther 2010 Oct;335(1):103-13
4-(5-(cyclopropylcarbamoyl)-2-methylphenylamino)-5-methyl-N-propylpyrrolo(1,2-f)(1,2,4)triazine-6-carboxamide  0   *Pyrroles *Triazines Mitogen-Activated Protein Kinase 14/antagonists & inhibitors. J Med Chem 2010 Sep 23;53(18):6629-39
N-ethoxymethyl-3-amino-1,2,4-benzotriazine-1,4-dioxide  0   *Cyclic N-Oxides *Triazines. Biosci Biotechnol Biochem 2010 Jun 23;74(6):1181-7
7,9-diamino-10-(3'-phenoxypropyloxy)-6,8,10-triazaspiro(4.5)deca-6,8-diene  0   *Spiro Compounds *Triazines. Int J Oncol 2010 Jul;37(1):211-8
BMS-690514  0   *Piperidines *Pyrroles *Triazines Carbon Radioisotopes. Br J Cancer. 2010 Jul 27;103(3):347-53
tris(triazolyl)triazine  0   *Triazines *Triazoles. Org Lett. 2010 Apr 2;12(7):1404-7
2,3,4,5-tetrahydro-4-(2-chlorophenyl)-2-phenyl-6-(pyrrolidin-1-yl)-1,2,4-triazin-5-one  0   *Pyrrolidines *Triazines. Bioorg Med Chem 2010 Mar 1;18(5):1816-21
PF 00277343  0   *Triazines. Bioorg Med Chem Lett 2010 Jan 1;20(1):306-8
1-(4-((4-(Dimethylamino)piperidin-1-yl)carbonyl)phenyl)-3-(4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl)urea  0   *Morpholines *Triazines Phosphatidylinositol 3-Kinases/antagonists & inhibitors. J Med Chem 2010 Mar 25;53(6):2636-45
PKF118-310  0   *Pyrimidinones *Triazines. Int J Cancer 2010 May 15;126(10):2426-36
4-(bis(2-methoxyethyl)amino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)pyrazolo(1,5-a)-1,3,5-triazine  0   *Pyrazoles *Triazines Corticotropin-Releasing Hormone/antagonists & inhibitors. J Pharm Sci 2009 Aug;98(8):2636-47
4,6-diamino-1,2-dihydro-2,2-dimethyl-1-(3-(2-chloro-4-trifluoromethoxyphenoxy)propyloxy)-1,3,5-triazine  0   *Triazines. PLoS Negl Trop Dis 2008;2(3):e190
2-amino-8-(1'-beta-D-2'-deoxyribofuranosyl)-imidazo(1,2-a)-1,3,5-triazin-4(8 H)-one  0   *Monosaccharides *Triazines. Angew Chem Int Ed Engl. 2010;49(1):177-80
6-(3-triethoxysilylpropylamino)-1,3,5-triazine-2,4-dithiol  0   *Sulfhydryl Compounds *Triazines. Molecules. 2009;14(10):4087-97
6-phenyl-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-5-one  0   *Triazines. Acta Crystallogr C. 2009 Dec;65(Pt 12):o593-7
BMS 754807  0   *Pyrazoles *Triazines. J Med Chem 2009 Dec 10;52(23):7360-3
(4-((1-(3-fluorophenyl)methyl)-1H-indazol-5-ylamino)-5-methylpyrrolo(2,1-f)(1,2,4)triazin-6-yl)carbamic acid 3-morpholinylmethyl ester  0   *Carbamates *Triazines Receptor, Epidermal Growth Factor/antagonists & inhibitors. J Med Chem 2009 Nov 12;52(21):6527-30
N-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-N-butyl-6-decyl-1,3,5-triazine-2,4-diamine  0   *Triazines. Toxicol In Vitro. 2009 Oct;23(7):1277-83
2-nitroimino-5-nitro-hexahydro-1,3,5-triazine  0   *Triazines. J Hazard Mater. 2009 Aug 15;167(1-3):205-8
N-octyl-6,6-dimethyl-N2-(4-methylbenzyl)-1,6-dihydro-1,3,5-triazine-2,4-diamine  0   *Triazines. J Antibiot (Tokyo) 2009 Sep;62(9):489-93
1,1',1''-(benzene-1,3,5-triyl)tripiperidine-4-carboxylic acid  0   *Nipecotic Acids *Triazines. Inorg Chem 2009 Sep 7;48(17):8057-9
4,6-dichloro-N-phenyl-1,3,5-triazin-2-amine  0   *Aniline Compounds *Triazines. Bioorg Med Chem 2009 Jul 15;17(14):5293-7
pyrrolotriazine-4-one  0   *Pyrroles *Triazines. Anal Biochem. 2009 Sep 1;392(1):59-69
pexacerfont  459856-18-9   *Pyrazoles *Triazines. Am J Physiol Gastrointest Liver Physiol. 2009 Jun;296(6):G1299-306
m-aminophenylamino-1,3,5-triazine  0   *Triazines. J Comb Chem. 2009 May-Jun;11(3):446-51
tris(2,3-dibromopropyl)isocyanurate  52434-90-9   *Triazines. Environ Sci Technol 2009 May 1;43(9):3080-6
2,4,6-tris(2-pyridyl)-1,3,5-triazine  0   *Pyridines *Triazines. J Am Chem Soc. 2009 Apr 29;131(16):5885-90
1,4-bis(4,6-diamino-1,3,5-triazin-2-yl)benzene  0   *Triazines. Chemphyschem 2009 Apr 14;10(6):896-900
2,4-dichloro-6-(p-(N,N-diethylamino)biphenylyl)-1,3,5-triazine  0   *Biphenyl Compounds *Triazines. J Phys Chem A. 2009 Apr 30;113(17):5066-72
GS26575  0   *Triazines. Mar Pollut Bull 2009 Jun;58(6):803-11
tradimefon  0   *Triazines. Spectrochim Acta A Mol Biomol Spectrosc. 2009 Apr;72(3):621-6
triazavirin  0   *Azoles *Triazines. Antibiot Khimioter. 2007;52(11-12):18-20
2-(3,4-dimethoxybenzyl)-7-((1R)-1-((1R)-1-hydroxyethyl)- 4-phenylbutyl)-5-methyl imidazo(5,1-f)(1,2,4)triazin-4 (3H)-one  0   *Imidazoles *Triazines. Eur J Pharmacol. 2008 Dec 14;600(1-3):98-104
methyl 2-(5-oxo-3,4-di-(2-pyridyl)-1,4,5,6-tetrahydro-1,2,4-triazine-6-ylidene)acetate  0   *Acetates *Triazines. Acta Pol Pharm 2008 Nov-Dec;65(6):789-91
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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