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Sulfhydryl Compounds

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Definition: Compounds containing the -SH radical.  do not confuse with SULFHYDRYL REAGENTS; /physiol permitted with only endogenous SH cpds; DF: SULFHYDRYL CPDS   
Examples Cysteine; Dimercaprol; Ergothioneine; Mercaptoethanol; Mercaptoethylamines; 3-Mercaptopropionic Acid; 6-Mercaptopurine; Mesna; Methimazole; S-Nitrosothiols; Pantetheine; Succimer; Thiocholine; Thioglycolates; Thiomalates 		Other names Thiols; Mercapto Compounds; Compounds, Sulfhydryl; Compounds, Mercapto; Mercaptans
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(methylthio)methanethiol  0   *Sulfhydryl Compounds *Sulfides. Proc Natl Acad Sci U S A. 2012 Feb 28;109(9):3492-7.
dimethyl-5-acetyl-4-methyl-6-(4-methylphenylimino)-6H-thiopyran-2,3-dicarboxylate  0   *Pyrans *Sulfhydryl Compounds Antineoplastic Agents. DNA Cell Biol. 2012 Jan;31(1):128-34
3-(methylamino)-2-((methylamino)methyl)propane-1-thiol  0   *Diamines *Sulfhydryl Compounds. Bioorg Med Chem Lett. 2011 Dec 15;21(24):7426-30.
ethyl 2-sulfanylacetate  0   *Acetates *Sulfhydryl Compounds Odors. J Agric Food Chem. 2011 Sep 28;59(18):10191-9
4(5)-(2-mercaptoethyl)-1H-imidazole-2-carboxamide  0   *Imidazoles *Sulfhydryl Compounds. J Am Chem Soc. 2011 Sep 14;133(36):14267-9
p,p'-dimercaptoazobenzene  0   *Sulfhydryl Compounds. Langmuir. 2011 Sep 6;27(17):10677-82
2-(hydroxymethylthio)ethanol  0   *Sulfhydryl Compounds. Nat Prod Commun. 2011 Aug;6(8):1131-2
2-((Z)-1-(3-furyl)methylidene)amino-1-benzenethiol  0   *Furans *Sulfhydryl Compounds. Analyst. 2011 May 7;136(9):1979-86
2-(((2-sulfanylphenyl)imino)methyl)phenol  0   *Phenols *Sulfhydryl Compounds. Analyst. 2011 May 7;136(9):1979-86
2-(3,4-dihydroxyphenyl)-1,3-dithialone  0   *Phenols *Sulfhydryl Compounds. Analyst. 2011 May 7;136(9):1965-70
2,5-dioxopyrrolidin-1-yl 2-(benzoylsulfanyl)acetate  0   *Acetates *Pyrrolidines *Sulfhydryl Compounds. Acta Crystallogr C. 2011 May;67(Pt 5):o166-70
2-(benzoylsulfanyl)acetic acid  0   *Acetates *Sulfhydryl Compounds. Acta Crystallogr C. 2011 May;67(Pt 5):o166-70
chitosan-6-mercaptonicotinic acid  0   *Sulfhydryl Compounds Chitosan/*analogs & derivatives Drug Carriers. Biomacromolecules 2009 Nov 9;10(11):3023-7
N-acetyl cysteine proline cysteine amide  0   *Oligopeptides *Sulfhydryl Compounds. Am J Respir Crit Care Med. 2011 Apr 15;183(8):1015-24
2-(4-(methylsulfonyl)phenyl)-3-(3(R)-oxocyclopentyl)propanoic acid  0   *Propionic Acids *Sulfhydryl Compounds Ligands. Chirality. 2011 Mar;23(3):277-80
poly(3,4-dihydroxycinnamic acid)-co-poly(4-hydroxycinnamic acid)-graft-dithiothreitiol copolymer  0   *Polyesters *Sulfhydryl Compounds Drug Carriers. J Control Release 2011 Jan 20;149(2):182-9
1,2-bis(phenylsulfonyl)ethane  0   *Ethylenes *Sulfhydryl Compounds. J Org Chem. 2011 Feb 4;76(3):1001-4
FBS 00831  0   *Pyrones *Sulfhydryl Compounds. Biochem Biophys Res Commun 2011 Jan 7;404(1):517-22
3-(allyltrisulfanyl)-2-aminopropanoic acid  0   *Sulfhydryl Compounds beta-Alanine/*analogs & derivatives. J Med Food. 2010 Oct;13(5):1247-53
2-(((dodecylsulfanyl)carbonothioyl)sulfanyl)-2-methylpropanoic acid  0   *Propionic Acids *Sulfhydryl Compounds. Acta Crystallogr C. 2010 Dec;66(Pt 12):o627-30
cyanoethenethiol  0   *Nitriles *Sulfhydryl Compounds. J Phys Chem A. 2010 Sep 9;114(35):9583-8
1-adamantanethiol  0   *Sulfhydryl Compounds Adamantane/*analogs & derivatives. ACS Nano 2010 Jul 27;4(7):3949-58
5-fluorofarnesylthiosalicylic acid  0   *Sulfhydryl Compounds *Benzoic Acids ras Proteins/antagonists & inhibitors. Eur J Pharmacol 2010 Sep 15;643(1):139-44
mercaptoacetyl polyethyleneimine  0   *Sulfhydryl Compounds Polyethyleneimine/*analogs & derivatives. Water Environ Res. 2010 Sep-Oct;82(9):790-6
1-(4-methylpent-2-enyl)-2-(4-phenylbut-2-enyl)disulfane  0   *Sulfhydryl Compounds. Molecules. 2010;15(8) (dup#8):5671-9
1-(2',4'-dinitroaminophenyl)-4,4,6-trimethyl-1,4-dihydropyrimidine-2-thiol  0   *Aniline Compounds *Sulfhydryl Compounds. Talanta 2010 May 15;81(3):1088-95
(4-mercaptophenyliminomethyl)-2-methoxyphenol  0   *Schiff Bases *Sulfhydryl Compounds. Talanta 2010 Jun 15;81(4-5):1176-82
1,1-bis(phenylsulfonyl)ethylene  0   *Ethylenes *Sulfhydryl Compounds. Chemistry. 2010 May 10;16(18):5354-61
3-mercapto-2,6-pyridinecarboxylic acid  0   *Picolinic Acids *Sulfhydryl Compounds. Chemistry 2010 Mar 22;16(12):3827-32
2-mercapto-4-methyl-5-thiazoleacetic acid  0   *Sulfhydryl Compounds *Thiazoles. Anal Chim Acta 2010 Mar 24;663(2):158-64
3-(2-thienyl)-2-sulfanylpropenoic acid  0   *Acrylates *Sulfhydryl Compounds. Inorg Chem 2010 Mar 1;49(5):2173-81
2-(2-naphthoxy)ethyl-2-(piperidino)ethanesulfonate  0   *Piperidines *Sulfhydryl Compounds. J Fluoresc. 2010 Jan;20(1):421-4
1-(4-(2-(4-bromobenzenesulfonamino) ethyl) phenylsulfonyl)-3-(trans-4-methylcyclohexyl)urea  0   *Sulfhydryl Compounds Urea/*analogs & derivatives. Arzneimittelforschung. 2009;59(11):550-6
N-(2-mercaptoethyl)octadecanamide  0   *Stearic Acids *Sulfhydryl Compounds. Phys Chem Chem Phys. 2010 Jan 14;12(2):345-57
6-(3-triethoxysilylpropylamino)-1,3,5-triazine-2,4-dithiol  0   *Sulfhydryl Compounds *Triazines. Molecules. 2009;14(10):4087-97
4,5-dimercaptocatechol  0   *Catechols *Sulfhydryl Compounds. Inorg Chem. 2009 Sep 21;48(18):8830-44
naphthalene-1,8-dithiolate  0   *Naphthalenes *Sulfhydryl Compounds. Chemistry. 2009 Aug 24;15(34):8518-25
1-cyano-2,3-epithiopropane  0   *Nitriles *Sulfhydryl Compounds Propane/*analogs & derivatives. Carcinogenesis. 2009 Oct;30(10):1754-62
4-((4-hydroxyphenyl)sulfanyl)but-3-en-2-one  0   *Phenylbutyrates *Sulfhydryl Compounds. J Med Chem. 2009 Aug 13;52(15):4973-6
4,4'-dithiodibenzoic acid  0   *Benzoates *Sulfhydryl Compounds. J Am Chem Soc. 2009 Jul 1;131(25):8833-8
2-dichloroamino-2-methyl-propane-1-sulfonic acid sodium salt  0   *Sulfhydryl Compounds. Bioorg Med Chem Lett 2009 May 15;19(10):2731-4
1,4-bis(2-hydroxyethylthio)butane  0   *Butanes *Sulfhydryl Compounds. Anal Bioanal Chem. 2009 Apr;393(8):1949-56
1,3-bis(2-hydroxyethylthio)propane  0   *Sulfhydryl Compounds Propane/*analogs & derivatives. Anal Bioanal Chem. 2009 Apr;393(8):1949-56
bis(2-hydroxyethylthio)methane  0   *Sulfhydryl Compounds Methane/*analogs & derivatives. Anal Bioanal Chem. 2009 Apr;393(8):1949-56
3-mercaptopropylphosphonic acid  0   *Phosphonic Acids *Sulfhydryl Compounds. Bioelectrochemistry. 2009 Apr;75(1):26-31
(2-mercaptophenylimino)-methyl-4,6-di-tert-butylphenolate(2-)  0   *Phenols *Sulfhydryl Compounds. Inorg Chem. 2009 Apr 20;48(8):3783-91
4H-thiopyran-4-one tetrahydro-3,5-bis-((4-nitrophenyl)methylene)-1,1-dioxide  0   *Pyrans *Sulfhydryl Compounds. J Biol Chem 2009 Mar 27;284(13):8369-81
2-mercapto-4-methylpyrimidine  0   *Pyrimidines *Sulfhydryl Compounds. J Immunol Methods 2009 Apr 15;343(2):119-29
4-methylbenzenethiol  0   *Sulfhydryl Compounds. Angew Chem Int Ed Engl. 2009;48(12):2180-4
bis(m-N,N-dimethylaminomethylphenyl)phosphinomethanethiol  0   *Phenylenediamines *Sulfhydryl Compounds. Bioorg Med Chem 2009 Feb 1;17(3):1055-63
5-chloro-2-mercaptobenzothiazole  0   *Sulfhydryl Compounds *Benzothiazoles. J Microbiol Methods. 2009 Mar;76(3):313-5
5-hydroxy-3-mercapto-2-pentanone  0   *Pentanones *Sulfhydryl Compounds. J Agric Food Chem 2008 Nov 26;56(22):10679-82
N,N,N-trimethyl(11-mercaptoundecyl)ammonium chloride  0   *Quaternary Ammonium Compounds *Sulfhydryl Compounds. Chemistry 2009;15(9):2032-5
3-(4-pyridine-4-yl-phenyl)-propane-1-thiol  0   *Pyridines *Sulfhydryl Compounds. Langmuir. 2009 Jan 20;25(2):959-67
poly(ethylene glycol)dithiol  0   *Polyethylene Glycols *Sulfhydryl Compounds. Acta Biomater 2009 Feb;5(2):570-9
1-phenylethyl mercaptan  0   *Sulfhydryl Compounds. J Agric Food Chem. 2009 Jan 14;57(1):239-44
4-pyridineethanethiolate  0   *Pyridines *Sulfhydryl Compounds. Phys Chem Chem Phys. 2008 Dec 14;10(46):6935-9
3-mercapto-5,6-diphenyl-1,2,4-triazine  0   *Triazines *Sulfhydryl Compounds. Protein Pept Lett 2008;15(10):1068-74
4-mercaptbutylphosphonic acid  0   *Organophosphorus Compounds *Sulfhydryl Compounds. Langmuir. 2008 Nov 18;24(22):13203-11
(4-amino-5-mercaptopentanoylamino)acetic acid  0   *Amino Acids *Sulfhydryl Compounds Glutamyl Aminopeptidase/antagonists & inhibitors. Biochem J 2008 Nov 15;416(1):37-46
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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