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Mesna

More information in Books or onNLM PubMed
Definition: A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.     
Pharmacological Action Protective Agents 		Other names Coenzyme M; 2-Mercaptoethanesulfonate; UCB3983; UCB 3983; Mesna Sanfer Brand; Mesna Kendrick Brand; MESNA cell; Bristol Myers Squibb Brand of Mesna; ASTAD 7093; ASTA D 7093; 2-Mercaptoethanesulphonate, Sodium; 2 Mercaptoethanesulfonate; cell pharm Brand of Mesna; Ziken; Uromitexan; UCB-3983; UCB Brand of Mesna; Sodium 2-Mercaptoethanesulphonate; Sanfer Brand of Mesna; MucofluidDrugs* : MESNEX; MESNA
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
12-aza-13-carboxy-14-hydroxy-11-oxo-3,4-dithiapentadecanesulfonic acid 14-phosphate  0   *Phosphoric Acid Esters Mesna/*analogs & derivatives. Chembiochem 2003 Apr 4;4(4):333-5
TIC protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Carboplatin Taxoids. Semin Oncol 2000 Feb;27(1 Suppl 1):36-40
MINT protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Mitoxantrone Taxoids. Invest New Drugs 1999;17(2):187-92
NaPIM protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Cisplatin Ifosfamide Vinblastine/analogs & derivatives. Cancer Chemother Pharmacol 1999;44 Suppl;S24-5
VACIME protocol  0   Mesna Doxorubicin Ifosfamide *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Etoposide Vincristine. Bone Marrow Transplant 1999 Sep;24(5):527-33
2-mercaptoethanesulfonic acid albumin  0   *Serum Albumin Mesna/*analogs & derivatives. Arzneimittelforschung 1998 Jun;48(6):691-3
VIMP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Vincristine Carboplatin. J Clin Oncol 1998 Aug;16(8):2708-14
MIZE protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Idarubicin. Leuk Lymphoma 1997 Aug;26(5-6):595-602
VIE protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Vincristine Epirubicin. Eur J Cancer 1995 Oct;31A(11):1773-7
MINE-BOP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Ifosfamide Mitoxantrone Prednisone Vincristine. Acta Oncol 1995;34(7):937-40
MINE protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Mitoxantrone. Invest New Drugs 1994;12(3):217-22
ICE protocol 5  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Carboplatin. Hum Gene Ther 1994 Jul;5(7):891-911
IVADIC regimen  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Dacarbazine Doxorubicin Ifosfamide Vincristine. Cancer Chemother Pharmacol 1992;30(2):100-4
MINE-ESHAP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cytarabine Etoposide Ifosfamide Methylprednisolone Hemisuccinate Mitoxantrone. Ann Oncol 1991;2 (Suppl 1):31
MAID protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Dacarbazine Doxorubicin Ifosfamide. J Clin Oncol 1989;7(9):1208
arginine 2-mercaptoethane sulfonate  106854-46-0   Arginine/*analogs & derivatives Mesna/*analogs & derivatives. Drugs Exp Clin Res 1988;14(7):473
VlhP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Ifosfamide. Cancer 1988;62(1):24
2-mercaptoethanesulfonate-cysteine disulfide  0   Cysteine/*analogs & derivatives Mesna/*analogs & derivatives. Clin Chim Acta 1981;111(1):47
2,2'-dithiodiethanesulfonic acid  45127-11-5 ethanesulfonic acid, 2,2'-dithiobis  Mesna/*analogs & derivatives. Anal Biochem 1980;106(2):363
acetylcoenzyme M  0   Mesna/*analogs & derivatives. Anal Biochem 1980;106(2):363
methyl coenzyme M methylreductase  EC 1.-   *Oxidoreductases Multienzyme Complexes Mesna. Appl Environ Microbiol 34(4):374;1977; Methods Enzymol 1980;67:545
methyl coenzyme M  53501-90-9 2-(methylthio)ethanesulfonate  Mesna/*analogs & derivatives. J Bacteriol 1980;141(2):728; J Biol Chem 1980;255(5):1891

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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