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Idarubicin

More information in Books or onNLM PubMed
Definition: An orally administered anthracycline antineoplastic. The compound has shown activity against breast cancer, lymphomas and leukemias, together with the potential for reduced cardiac toxicity.     
Pharmacological Action Antibiotics, Antineoplastic 		Other names 4-Demethoxydaunorubicin; NSC256439; NSC 256439; IMI30; Hydrochloride, Idarubicin; 4 Desmethoxydaunorubicin; 4 Demethoxydaunorubicin; IMI 30; NSC-256439; Idarubicin Hydrochloride; 4-Desmethoxydaunorubicin; IMI-30Drugs* : IDARUBICIN HYDROCHLORIDE; IDAMYCIN; IDAMYCIN PFS; IDARUBICIN HYDROCHLORIDE PFS
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
EORTC GIMEMA AML-13 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone Idarubicin. Haematologica 2007 May;92(5):605-11
EORTC GIMEMA AML-10 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Etoposide Mitoxantrone Idarubicin. Haematologica 2007 May;92(5):605-11
MATILDE regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Methotrexate Thiotepa Idarubicin. Neurology 2006 May 9;66(9):1435-8
8-hydroxy-8-methylidarubicinone  0   Idarubicin/*analogs & derivatives. Bioorg Med Chem. 2004 Jun 1;12(11):2863-6
TCID protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Dexamethasone Thalidomide Idarubicin. Ann Hematol 2004 Jul;83(7):467-70
VID protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Vincristine Idarubicin. Ann Hematol 2004 Jul;83(7):467-70
ICBV regimen  0   *Antineoplastic Combined Chemotherapy Protocols Carmustine Cyclophosphamide Etoposide Idarubicin. Int J Hematol 2004 Jan;79(1):85-91
CIOD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Dexamethasone Vincristine Idarubicin. Ann Oncol l2003 Dec;14(12):1792-4
idarubicinone  0   Idarubicin/*analogs & derivatives. J Org Chem 2003 Mar 21;68(6):2398-404
DIZE protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Etoposide/analogs & derivatives Ifosfamide Idarubicin. Leuk Lymphoma 1999 Nov;35(5-6):641-2
FLU-ID regimen  0   *Antineoplastic Combined Chemotherapy Protocols Vidarabine/analogs & derivatives Idarubicin. Haematologica 1999 Nov;84(11):1002-6
Ida-FLAG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Vidarabine/*analogs & derivatives Idarubicin Granulocyte Colony-Stimulating Factor. Ann Hematol 1999 Sep;78(9):418-25
GIMEMA ALL 0394  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Idarubicin. Haematologica 1999 Mar;84(3):222-5
VICED protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Etoposide Vincristine Idarubicin. Leuk Lymphoma 1998 Jun;30(1-2):153-62
CIOP-Bleo protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Prednisone Vincristine Idarubicin. Anticancer Drugs 1997 Nov;8(10):937-42
MIZE protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Idarubicin. Leuk Lymphoma 1997 Aug;26(5-6):595-602
FLIDA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Prednisone Vidarabine/analogs & derivatives Idarubicin. Henatol Oncol 1997 Feb;15(1):27-31
VICOP-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Etoposide Prednisone Vincristine Idarubicin. Haematologica 1997 May-Jun;82(3):309-13
AIDA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Tretinoin Idarubicin. Blood 1997 Aug 1;90(3):1014-21
IIVP-16  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Idarubicin. Leuk Lymphoma 1997 Feb;24(5-6):513-22
CIP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Prednisone Idarubicin. Leuk Lymphoma 1997 Jan;24(3-4):355-61
8-fluoroidarubicin  0   Idarubicin/analogs & derivatives. Mol Pharmacol 1996 Mar;49(3):532-9
IVAP protocol  0   Asparaginase *Antineoplastic Combined Chemotherapy Protocols Prednisolone Vincristine Idarubicin. Semin Oncol 1993 Dec;20(6 Suppl 8):39-46
ETI protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Thioguanine Idarubicin. Leukemia 1994 Jan;8(1):11-5
ICE protocol 4  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Idarubicin. Bone Marrow Transplant 1993 Sep;12(3):267-71
LAI regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Idarubicin. Hematol Oncol 1993 Mar-Apr;11(2):73-80
CIOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Prednisolone Vincristine Idarubicin. Leuk Lymphoma 1993;10 Suppl:39-41
4-demethoxydaunomycinone  60660-75-5 5,12-Naphthacenedione, 9-acetyl-7,8,9,10-tetrahydro-6,7,9,11-tetrahydroxy-, (7S-cis)  Idarubicin/*analogs & derivatives. Cancer Chemother Pharmacol 1992;30(4):303-6
ALL-1 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Cyclophosphamide Prednisone Vincristine Idarubicin. Semin Hematol 1991 Jul;28(3 Suppl 4):72-5
13-methyl-13-dihydro-4-demethoxydaunorubicin  111248-05-6   Idarubicin/*analogs & derivatives. Chem Pharm Bull (Tokyo) 1986;34(11):4613
9-O-daunosaminyl-4-demethoxydaunorubicin  99457-12-2   Idarubicin/*analogs & derivatives. J Antibiot (Tokyo) 1985;38(9):1277
4-demethoxy-10,10-dimethyldaunomycin  91003-74-6   Idarubicin/*analogs & derivatives. J Med Chem 1984;27(10):1343
4-demethoxydaunorubicin bis(hydrazone)  77313-12-3 Pentanedioic acid, 3-amino-, bis((1-(4-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-1,2,3,4,6,11-hexahydro-2,5,12-trihydroxy-6,11-dioxo-2-naphthacenyl)ethylidene)hydrazide), trihydrochloride, (2S-(2alpha,2(2R*,4R*),4alpha))  Idarubicin/*analogs & derivatives. Cancer Res 1983;43(6):2880
4-demethoxy-11-deoxydaunomycin  77312-66-4 5,12-Naphthacenedione, 9-acetyl-7-((3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,9-dihydroxy-, (7S-cis)  Idarubicin/*analogs & derivatives. J Antibiot (Tokyo)1980;33(12):1581

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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