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Mitoxantrone

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Definition: An anthracenedione-derived antineoplastic agent.     
Pharmacological Action Analgesics; Antineoplastic Agents 		Other names Mitozantrone; NSC301739D; NSC301739; NSC299195; NSC287836; NSC279836; NSC 301739D; NSC 301739; NSC 299195; NSC 287836; NSC 279836; Hydrochloride, Mitoxantrone; CL232325; CL 232325; Acetate, Mitoxantrone; Wyeth Brand of Mitoxantrone Hydrochloride; Ralenova; Pralifan; Onkotrone; NovantroneDrugs* : MITOXANTRONE HYDROCHLORIDE; NOVANTRONE
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BBR3378  0   Mitoxantrone/*analogs & derivatives Antineoplastic Agents. Clin Immunol. 2011 Dec;141(3):304-16
mitoxantrone 4'-beta-D-glucoside  0   *Glucosides Mitoxantrone/*analogs & derivatives. Org Lett. 2011 May 20;13(10):2786-8
WRC 213  0   Methionine/*analogs & derivatives Mitoxantrone/*analogs & derivatives DNA Topoisomerases, Type II/antagonists & inhibitors. Biochem Pharmacol 2008 Feb 15;75(4):847-56
EORTC GIMEMA AML-13 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone Idarubicin. Haematologica 2007 May;92(5):605-11
EORTC GIMEMA AML-10 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Etoposide Mitoxantrone Idarubicin. Haematologica 2007 May;92(5):605-11
R-FCM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone Vidarabine/analogs & derivatives Antibodies, Monoclonal, Murine-Derived. Leukemia 2007 Mar;21(3):524-8
LPA97R protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone Tretinoin. Leukemia 2007 Mar;21(3):446-52
MRC AML 10 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Amsacrine Cytarabine Daunorubicin Etoposide Mitoxantrone. Pediatr Blood Cancer 2007 Mar;48(3):262-7
MEA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone. Bone Marrow Transplant 2002 Dec;30(12):971-3
VEPEMB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone Procarbazine Vinblastine. Tumori 2002 Jan-Feb;88(1 Suppl 1):S29-31
RIME regimen  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Mitoxantrone Antibodies, Monoclonal, Murine-Derived. Eur J Haematol Suppl 2001 Jul;(64):56-62
MAC chemotherapy protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Mitoxantrone. Blood 2001 Sep 1;98(5):1302-11
MECA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone Carboplatin. Leuk Lymphoma 2000 Nov;39(5-6):613-24
MIFAP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Cytarabine Mitoxantrone Vidarabine/analogs & derivatives. J Cancer Res Clin Oncol 2001;127(6):387-95
CMC protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone Cladribine. Eur J Haematol 2001 Mar;66(3):188-94
TAM protocol  0   Mitoxantrone *Antineoplastic Combined Chemotherapy Protocols Cytarabine Topotecan. Ann N Y Acad Sci 2000;922:326-9
MiCMA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Methylprednisolone Mitoxantrone Carboplatin. Ann Oncol. 2000 Jul;11(7):867-71
CN3OP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Prednisone Mitoxantrone Vincristine. Med Oncol 2000 Aug;17(3):195-202
MINT protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Mitoxantrone Taxoids. Invest New Drugs 1999;17(2):187-92
FLAM regimen  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Mitoxantrone Vidarabine/analogs & derivatives. Cancer 1999 Dec 1;86(11):2246-51
MCP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Chlorambucil Mitoxantrone Prednisolone. Clin Oncol (R Coll Radiol)1999;11(3):184-6
GEMIA protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Etoposide Mitoxantrone. Haematologica 1999 Mar;84(3):226-30
CMD protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Mitoxantrone Cladribine. Leuk Lymphoma 1999 Jan;32(3-4):359-63
OPEN protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Mitoxantrone Prednisone Vincristine. Blood 1999 Apr 1;93(7):2202-7
MVC protocol 2  0   *Antineoplastic Combined Chemotherapy Protocols Lomustine Mitoxantrone Vinblastine. Cancer J Sci Am 1998 Jul-Aug;4(4):254-60
MCNO regimen  0   *Antineoplastic Combined Chemotherapy Protocols Methotrexate Mitoxantrone Vincristine Carboplatin. Oncology 1998 Mar-Apr;55(2):139-44
PMitCEBO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Etoposide Mitoxantrone Prednisolone Vincristine. Acta Oncol 1997;36(6):573-6
MLL-93 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Asparaginase Leucovorin Cyclophosphamide Cytarabine Dexamethasone Etoposide Hydrocortisone Hydroxyurea Methotrexate Mitoxantrone. Leuk Res 1997 Sep;21(9):811-5
(mitoxantrone)cerium(IV)  0   *Organometallic Compounds Mitoxantrone/*analogs & derivatives Cerium. J Inorg Biochem 1997 Nov 1;68(2):117-21
MIMO protocol  0   *Antineoplastic Combined Chemotherapy Protocols Methotrexate Mitoxantrone Vincristine. Oncology 1997 Sep-Oct;54(5):371-5
NCVB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Mitoxantrone Vincristine. J Clin Oncol 1997 Mar;15(3):1131-7
MAD protocol  0   Cytarabine *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Mitoxantrone Granulocyte Colony-Stimulating Factor. J Clin Oncol 1997 Feb;15(2):491-8
BF-9 protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Daunorubicin Etoposide Mitoxantrone Thioguanine. Eur J Obstet Gynecol Reprod Biol 1995 Dec;63(2):139-41
FMN regimen  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Mitoxantrone Vinblastine/analogs & derivatives. J Infus Chemother 1996 Spring;6(2):102-6
FLANG protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cytarabine Mitoxantrone Vidarabine/analogs & derivatives Granulocyte Colony-Stimulating Factor. Leuk Lymphoma 1996 Jun;22(1-2):173-6
TEMP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cisplatin Etoposide Mitoxantrone Tamoxifen. Cancer 1996 Nov 1;78(9):1906-11
PmM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Prednimustine. Leukemia 1996 May;10(5):836-43
mitoxantrone-copper(II)  0   *Organometallic Compounds Mitoxantrone/*analogs & derivatives Copper. J Inorg Biochem 1996 May 1;62(2):137-45
TNT protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Thiotepa Taxoids. Ann N Y Acad Sci 1995 Dec 29;770:288-304
MITT protocol  0   Mitoxantrone *Antineoplastic Combined Chemotherapy Protocols Thiotepa. Ann N Y Acad Sci 1995 Dec 29;770:288-304
P-COMM-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Methotrexate Mitoxantrone Prednisolone Vincristine. Leuk Lymphoma 1995 Jun;18(1-2):137-43
MINE-BOP protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Ifosfamide Mitoxantrone Prednisone Vincristine. Acta Oncol 1995;34(7):937-40
HD-CNV protocol  0   Etoposide *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone. J Clin Oncol 1995 Oct;13(10):2483-9
CNV protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone Vincristine. J Clin Oncol 1995 Oct;13(10):2483-9
FMP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Prednisone Vidarabine/analogs & derivatives. Eur J Haematol 1995 Oct;55(4):262-6
MMIP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Ifosfamide Methotrexate Mitoxantrone Prednisolone. Rinsho Katsueki 1995 Feb;36(2):106-14
VIMB protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Etoposide Ifosfamide Mitoxantrone. J Clin Oncol 1995 Apr;13(4):953-60
MINE protocol  0   Mesna *Antineoplastic Combined Chemotherapy Protocols Etoposide Ifosfamide Mitoxantrone. Invest New Drugs 1994;12(3):217-22
cyclone protocol  0   *Antineoplastic Combined Chemotherapy Protocols Cyclophosphamide Mitoxantrone. Can Vet J 1994 Nov;35(11):706-8
MVPP-Bleo protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Mitoxantrone Prednisone Procarbazine Vincristine. Leuk Lymphoma 1994 Sep;15(1-2):153-7
T-NOP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Prednisone Thiotepa Vincristine. Semin Oncol 1995 Feb;22(1 Suppl 1):21-4
TMJ protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Thiotepa Carboplatin. J Med 1994;25(3-4):241-50
3M protocol  0   *Antineoplastic Combined Chemotherapy Protocols Methotrexate Mitomycins Mitoxantrone. Br J Cancer 1994 Nov;70(5):980-3
PEN protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Mitoxantrone Prednisone. Semin Hematol 1994 Apr;31(2 Suppl 3):23-9
MVF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Mitoxantrone Vincristine. Breast Cancer Res Treat 1993 Dec;28(3):291-4
NOPP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Prednisone Procarbazine Vincristine. Ann Oncol 1994;5 Suppl 2;73-7
VNCOP-B protocol  0   *Antineoplastic Combined Chemotherapy Protocols Bleomycin Cyclophosphamide Etoposide Mitoxantrone Prednisone Vincristine. Haematologica 1993 Nov-Dec;78(6):378-82
FND protocol  0   *Antineoplastic Combined Chemotherapy Protocols Dexamethasone Mitoxantrone Vidarabine/analogs & derivatives. J Clin Oncol 1994 Mar;12(3):575-9
MFL combination  0   *Antineoplastic Combined Chemotherapy Protocols Leucovorin Fluorouracil Mitoxantrone. Am J Clin Oncol 1994 Feb;17(1):45-9
MECP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Mitoxantrone Prednisolone Carboplatin. Gan To Kagaku Ryoho 1994 Feb;21(2):237-41
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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