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Prednimustine

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Definition: Ester of CHLORAMBUCIL and PREDNISOLONE used as a combination alkylating agent and synthetic steroid to treat various leukemias and other neoplasms. It causes gastrointestinal and bone marrow toxicity.     
Pharmacological Action Antineoplastic Agents, Alkylating 		Other names NSC134087; NSC 134087; Leo1031; Leo 1031; St+¬r+¬ocyt; Stereocyt; Sterecyt; Pharmacia Brand of Prednimustine; NSC-134087; Leo-1031
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PmM protocol  0   *Antineoplastic Combined Chemotherapy Protocols Mitoxantrone Prednimustine. Leukemia 1996 May;10(5):836-43
VMP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Mitoxantrone Prednimustine. J Clin Oncol 1992 Feb;10(2):228-32
IMEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Glyoxal Ifosfamide Prednimustine. Eur J Haematol 1991;46(5):306
VAP regimen  0   *Antineoplastic Combined Chemotherapy Protocols Doxorubicin Prednimustine Vincristine. Chemioterapia 1987;6(6):393
PNMF protocol  0   *Antineoplastic Combined Chemotherapy Protocols Fluorouracil Methotrexate Mitoxantrone Prednimustine. Semin Oncol 1986;13(1 Suppl 1):39
CEP protocol  0   *Antineoplastic Combined Chemotherapy Protocols Etoposide Lomustine Prednimustine. Semin Oncol 1985;12(1 Suppl 2):23

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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