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Benzothiazoles

More information in Books or onNLM PubMed
Definition: Compounds with a benzene ring fused to a thiazole ring.     
Examples Dithiazanine; Ethoxzolamide; Riluzole; Saccharin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-((7-methoxy-5-oxo-2,3,5,11a-tetrahydro-1H-benzo(e)pyrrolo(1,2-a)(1,4)diazepin-8-yl)oxy)hexyl-1,2-dihydro-1gamma6-naphtho(1,8-cd)isothiazole-1,1-dione  0   *Benzodiazepinones *Benzothiazoles. Bioorg Med Chem. 2012 Jan 15;20(2):789-800.
O-ethyl S-(5-(5-(tert-butyl)-2-oxo-1,3,4-thiadiazol-3(2H)-yl)-6-fluorobenzothiazol-2-yl)carbonothioate  0   *Benzothiazoles. Bioorg Med Chem. 2012 Jan 1;20(1):296-304
erythrazole B  0   Benzothiazoles Antineoplastic Agents Terpenes. Org Lett. 2011 Dec 16;13(24):6580-3
erythrazole A  0   *Benzothiazoles Antineoplastic Agents Terpenes. Org Lett. 2011 Dec 16;13(24):6580-3
2-(4-(dimethylamino)styryl)-3-methylbenzo(d)thiazol-3-ium  0   *Styrenes *Benzothiazoles. Spectrochim Acta A Mol Biomol Spectrosc. 2011 Oct 15;81(1):449-57.
4-(2-(2-hydroxycyclohexylamino)benzothiazol-6-yloxy)pyridine-2-carboxylic acid methylamide  0   *Picolinic Acids *Benzothiazoles Receptor, Macrophage Colony-Stimulating Factor/antagonists & inhibitors. Int J Toxicol 2011 May;30(3):300-12
3-chloro-3'-((2-cyclopentyl-3-oxo-2,3-dihydrobenzo(d)isothiazol-6-yloxy)methyl)biphenyl-4-carboxylic acid  0   *Chlorobenzoates *Benzothiazoles Receptors, Metabotropic Glutamate/agonists. J Med Chem 2011 Jan 13;54(1):342-53
2-chloro-1,3-dibenzothiazolinecyclohexene  0   *Cyclohexanes *Benzothiazoles. Cell Biochem Funct 2011 Jul;29(5):400-7
9,9'-bis(6''N,N,N-trimethy-lammonium)hexylfluorene-co-alt-4,7-(2,1,3-benzothiadiazole)dibromide  0   *Fluorenes *Benzothiazoles. J Phys Chem A. 2011 Jun 23;115(24):6376-82
2-(3,5-dihydroxyphenyl)-6-hydroxybenzothiazole  0   *Benzothiazoles. DNA Cell Biol. 2011 Aug;30(8):617-21
2-(4'-methylaminophenyl)-6-fluorobenzothiazole  0   *Benzothiazoles. Bioorg Med Chem. 2011 May 1;19(9):2980-90
(4'-methylaminophenyl)-6-fluorobenzothiazole  0   *Benzothiazoles. Bioorg Med Chem. 2011 May 1;19(9):2918-26
2-benzo(1,3)dioxol-5-yl-N-(2-(benzothiazol-4-yloxymethyl)phenyl)-N-benzylacetamide  0   *Acetanilides *Benzothiazoles NF-kappa B/antagonists & inhibitors. Biochem Biophys Res Commun 2011 May 20;408(4):625-9
imidazo(2,1-b)(1,3)benzothiazole  0   *Imidazoles *Benzothiazoles. Eur J Med Chem. 2011 May;46(5):1874-81
N-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide  0   *Sulfonamides *Benzothiazoles. J Med Chem 2011 Mar 24;54(6):1789-811
N-(6-ethoxybenzo(d)thiazol-2-yl)cyclohexanecarbothiamide  0   *Benzothiazoles. Med Chem 2010 May 1;6(3):159-64
N-(6-ethoxybenzo(d)thiazol-2-yl)cyclohexanecarboxamide  0   *Benzothiazoles. Med Chem 2010 May 1;6(3):159-64
3-(2-(azepan-1-yl)ethyl)-6-propylbenzo(d)thiazol-2(3H)-one  0   *Azepines *Benzothiazoles Ligands Tritium. Eur J Pharmacol 2011 Feb 25;653(1-3):1-7
CX 5461  0   *Naphthyridines *Benzothiazoles RNA Polymerase I/antagonists & inhibitors. Cancer Res 2011 Feb 15;71(4):1418-30
N-(2-(dimethylamino)ethyl)-2-aminothiazonaphthalimide  0   *Benzothiazoles *Naphthalimides. Mol Cancer Res 2010 Dec;8912):1619-32
SSJ 127  0   *Oxazoles *Benzothiazoles. Bioorg Med Chem 2010 Nov 15;18(22):7804-8
2-(4'-(dimethylamino)phenyl)benzothiazole  0   *Aniline Compounds *Benzothiazoles. J Fluoresc 2010 Jul;20(4):881-9
PMX 464  0   *Hydroquinones *Benzothiazoles. Eur J Pharmacol 2010 Sep 25;643(2-3):188-94
3-(benzothiazol-2-ylsulfanyl)acrylic acid ethyl ester  0   *Acrylates *Benzothiazoles. Bioorg Med Chem 2010 Jun 15;18(12):4178-86
3H-1,3-benzothiazole-2-thione  0   *Thiones *Benzothiazoles. J Phys Chem A. 2010 Jun 3;114(21):6336-41
poly((9,9-dioctylfluorene)-2,7-diyl-alt-(4,7-bis(3-hexylthien-5-yl)-2,1,3-benzothiadiazole)-2',2''-diyl)  0   *Polymers *Benzothiazoles. Nano Lett 2010 Apr 14;10(4):1302-7
2-(4-(dimethylamino)styryl)benzothiazole  0   *Styrenes *Benzothiazoles. J Colloid Interface Sci 2010 Apr 1;344(1):97-104
1-methyl-2-((3-methylbenzo(d)thiazol-2(3H)-ylidene)methyl)naphtho(1,2-d)thiazol-1-ium  0   *Benzothiazoles. Spectrochim Acta A Mol Biomol Spectrosc 2010 May;75(5):1605-9
6-methyl-2-(4'-fluorophenyl)-1,3-benzothiazole  0   *Benzothiazoles Fluorine Radioisotopes. J Med Chem 2009 Mar 12;52(5):1428-37
2-(4'-(methylamino)phenyl)-6-(2-fluoroethoxy)benzothiazole  0   *Benzothiazoles Fluorine Radioisotopes. Appl Radiat Isot 2010 Jun;68(6):1066-72
TMC 240  0   *Sulfones *Benzothiazoles. Eur J Pharm Biopharm 2010 Feb;74(2):233-8
3-(2-benzothiazolylthio)-1-propanesulfonic acid  0   *Alkanesulfonic Acids *Benzothiazoles Triose-Phosphate Isomerase/antagonists & inhibitors. Phys Chem Chem Phys. 2010 Mar 7;12(9):2067-74
3-(4-bromophenyl)-6-nitrobenzo(1.3.2)dithiazolium ylide 1,1-dioxide  0   *Cyclic S-Oxides *Benzothiazoles Cyclooxygenase 2. Bioorg Med Chem. 2010 Jan 15;18(2):597-604
N6-(2-(4-(isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo(d)thiazole-2,6-dione  0   *Isoquinolines *Benzothiazoles. J Med Chem 2010 Feb 11;53(3):1023-37
3-(4-(benzo(d)thiazol-2-yl)-1-phenyl-1H-pyrazol-3-yl)phenyl acetate  0   *Pyrazoles *Benzothiazoles. Chem Biol Interact. 2010 Feb 12;183(3):341-8
2-((3-ethyl-5-(2-(3-methylbenzo(d)thiazol-2(3H)-ylidene)ethylidene)-4-oxothiazolidin-2-ylidene)methyl)-5-fluoro-3-methylbenzo(d)thiazol-3-ium  0   *Benzothiazoles. J Med Chem 2010 Jan 14;53(1):368-73
2,3-dihydro-1,3-benzothiazol-2-iminium monohydrogen sulfate  0   *Imines *Benzothiazoles. Acta Crystallogr C. 2009 Dec;65(Pt 12):o624-9
2-iminio-2,3-dihydro-1,3-benzothiazole-6-sulfonate  0   *Imines *Benzothiazoles. Acta Crystallogr C. 2009 Dec;65(Pt 12):o624-9
4-(benzothiazol-2-yl)phenylnitrenium  0   *Benzothiazoles. Org Lett. 2009 Nov 5;11(21):4862-5
((5-(2-methylbenzothiazol-5-yloxymethyl)isoxazole-3-carbonyl)amino)phenylacetic acid methyl ester  0   *Phenylacetates *Benzothiazoles. J Med Chem 2009 Nov 12;52(21):6757-67
2-(2-(2,3,5,6,8,9,11,12,14,15-decahydro-1,4,7,10-,13,16-benzohexaoxacyclooctandecin)ethenyl)-3-methylbenzothiazolium  0   *Crown Ethers *Benzothiazoles. Luminescence 2009 Jul-Aug;24(4):236-42
2-phenoxymethylbenzothiazole  0   *Benzothiazoles. Spectrochim Acta A Mol Biomol Spectrosc 2009 Sep 15;74(1):132-9
2-(2'-hydroxy-3'-methoxyphenyl)benzothiazole  0   *Benzothiazoles. Spectrochim Acta A Mol Biomol Spectrosc 2009 Sep 15;74(1):30-5
AC220 compound  0   *Benzothiazoles *Phenylurea Compounds. Blood 2009 Oct 1;114(14):2984-92
AZD-3199  0   *Benzothiazoles Receptors, Adrenergic, beta-2/agonists. Expert Opin Ther Pat. 2009 Aug;19(8):1157-63
NSC 333003  0   *Hydrazines *Benzothiazoles. Bioorg Med Chem Lett 2009 Jul 15;19(14):3756-9
N1-(6-methoxy-1,3-benzothiazol-2-yl)-2-((5,5-dioxo-10-phenyl-5,10-dihydro-5gamma6-benzo(e)(1,2,4)triazolo(4,3-b)(1,2,4)thiadiazin-3-yl)sulfanyl)acetamide  0   *Sulfones *Benzothiazoles. Chem Biol Drug Des 2009 Jun;73(6):687-93
(2E)-N-(1,3-benzothiazol-2-yl)-3-(2,5-dimethoxyphenyl)-2-propenamide  0   *Amides *Benzothiazoles. Arzneimittelforschung. 2009;59(4):207-11
3-methyl-2-benzothiazolinone hydrazine hydrochloride  0   *Hydrazines *Benzothiazoles Indicators and Reagents. Acta Pharm. 2008 Mar;58(1):111-8
AC 93253  0   *Benzothiazoles. Biochem Biophys Res Commun 2009 Sep 4;386(4):729-33
(18)F-GE067  0   *Benzothiazoles Radiopharmaceuticals. J Nucl Med. 2009 May;50(5):818-22
S26948  0   *Benzothiazoles. Eur J Pharmacol 2009 Apr 17;608(1-3):104-11
(6-methyl-3-(4,5,7-trifluorobenzothiazol-2-ylmethyl)pyrrolo(2,3-b)pyridin-1-yl)acetic acid  0   *Benzothiazoles Aldehyde Reductase/antagonists & inhibitors. Bioorg Med Chem Lett 2009 Apr 1;19(7):2006-8
N-(dimethylthiocarbamoyl)benzo-thiazole-2-thione  0   *Thiones *Benzothiazoles. Acta Crystallogr B. 2009 Apr;65(Pt 2):107-25
2-(4-methylphenyl)imidazo(2,1-b)-5,6,7,8-tetrahydrobenzothiazole  0   *Imidazoles *Benzothiazoles. Biochemistry (Mosc) 2009 Feb;74(2):130-6
2-amino-4,5,6,7-tetrahydrobenzothiazole  0   *Benzothiazoles. Biochemistry (Mosc) 2009 Feb;74(2):130-6
6-(4-fluorophenyl)-2-methyl-N-(2-methylbenzothiazol-5-yl)nicotinamide  0   *Benzothiazoles Niacinamide/*analogs & derivatives. Bioorg Med Chem Lett 2008 Oct 15;18(20):5609-13
3-amino-4-(2,4,5-trifluorophenyl)-N-(4-(6-(2-methoxyethoxy)benzothiazol-2-yl)tetrahydropyran-4-yl)butanamide  0   *Benzothiazoles.
Pharma Action Dipeptidyl-Peptidase IV Inhibitors 		Bioorg Med Chem Lett 2008 Oct 15;18(20):5435-8
2-(6-(methylamino)pyridin-3-yl)-1,3-benzothiazol-6-ol  0   *Aminopyridines *Benzothiazoles Ligands. J Neurochem 2009 Mar;108(5):1177-86
2-(4'-fluorophenyl)-1,3-benzothiazole  0   *Benzothiazoles. Bioorg Med Chem Lett. 2009 Feb 1;19(3):602-5
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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