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Triose-Phosphate Isomerase

More information in Books or onNLM PubMed
Definition: An enzyme that catalyzes reversibly the conversion of D-glyceraldehyde 3-phosphate to dihydroxyacetone phosphate. A deficiency in humans causes nonspherocytic hemolytic disease (ANEMIA, HEMOLYTIC, CONGENITAL NONSPHEROCYTIC). EC 5.3.1.1.  /defic: consider also ANEMIA, HEMOLYTIC, CONGENITAL NONSPHEROCYTIC   
See Also Anemia, Hemolytic, Congenital Nonspherocytic 		Other names Triosephosphate Mutase; Triosephosphate Isomerase; Phosphotriose Isomerase; Triose Phosphate Isomerase; Mutase, Triosephosphate; Isomerase, Triosephosphate; Isomerase, Triose-Phosphate; Isomerase, Phosphotriose
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-(2-benzothiazolylthio)-1-propanesulfonic acid  0   *Alkanesulfonic Acids *Benzothiazoles Triose-Phosphate Isomerase/antagonists & inhibitors. Phys Chem Chem Phys. 2010 Mar 7;12(9):2067-74
6,6'-bisbenzothiazole-2,2'-diamine  0   *Thiazoles Triose-Phosphate Isomerase/antagonists & inhibitors. Biochemistry 2006 Feb 28;45(8):2556-60
PGK-TIM fusion protein, Thermotoga maritima  0   *Bacterial Proteins *Multienzyme Complexes *Phosphoglycerate Kinase *Triose-Phosphate Isomerase. Biol Chem 1997 Jul;378(7):679-85
tigA protein, Phytophthora infestans  0   *Glyceraldehyde-3-Phosphate Dehydrogenases *Triose-Phosphate Isomerase. J Bacteriol 1997 Nov;179(21):6816-23

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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