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Receptors, Adrenergic, beta-2

More information in Books or onNLM PubMed
Definition: A subclass of beta-adrenergic receptors (RECEPTORS, ADRENERGIC, BETA). The adrenergic beta-2 receptors are more sensitive to EPINEPHRINE than to NOREPINEPHRINE and have a high affinity for the agonist TERBUTALINE. They are widespread, with clinically important roles in SKELETAL MUSCLE; LIVER; and vascular, bronchial, gastrointestinal, and genitourinary SMOOTH MUSCLE.      Other names beta-2 Adrenergic Receptors; Receptors, beta-2 Adrenergic; Adrenergic beta-2 Receptors; beta-2 Receptors, Adrenergic; beta-2 Adrenergic Receptor; Receptors, beta 2 Adrenergic; Receptors, Adrenergic beta-2; Receptor, beta-2 Adrenergic; Adrenergic beta 2 Receptors; Adrenergic Receptors, beta-2; Adrenergic Receptor, beta 2; beta 2 Adrenergic Receptors; Receptor, Adrenergic, beta-2; Adrenergic Receptor, beta-2
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ADRB2 protein, human  0   *Receptors, Adrenergic, beta-2. J Mol Model. 2010 Aug;16(8):1307-18
N-((4'-hydroxybiphenyl-3-yl)methyl)-2-(3-(2-((-2-hydroxy-2-(4-hydroxy-3-((methylsulfonyl)amino)phenyl)ethyl)amino)-2-methylpropyl)phenyl)acetamide  0   *Sulfonamides *Benzeneacetamides Receptors, Adrenergic, beta-2. J Med Chem 2010 Sep 23;53(18):6640-52
4-(2-((6-((2-(((2,6-dichlorophenyl)methyl)oxy)ethyl)oxy)hexyl)amino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol  0   *Benzyl Alcohols *Chlorobenzenes Receptors, Adrenergic, beta-2. J Med Chem 2010 Jun 10;53(11):4522-30
AZD-3199  0   *Benzothiazoles Receptors, Adrenergic, beta-2/agonists. Expert Opin Ther Pat. 2009 Aug;19(8):1157-63
3-(4-((6-((-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethyl)amino)hexyl)oxy)butyl)benzenesulfonamide  0   *Sulfonamides 2-Hydroxyphenethylamine/*analogs & derivatives Receptors, Adrenergic, beta-2/agonists. J Med Chem 2009 Apr 23;52(8):2280-8
4-(2-hydroxy-3-isopropylaminopropoxy)-7-amino-6-iodofluorenone  0   *Fluorenes Receptors, Adrenergic, beta-2/antagonists & inhibitors. Biochemistry. 2000 Oct 24;39(42):13044-52
vanidipinedilol  0   *Dihydropyridines Receptors, Adrenergic, beta-2/agonists. J Cardiovasc Pharmacol 2000 Jan;35(1):51-63
sibenadet  0   *Thiazoles Receptors, Dopamine D2/agonists Receptors, Adrenergic, beta-2/agonists. J Med Chem 1998 Dec 3;41(25):4915-7
vanidilol  0   *Benzaldehydes Receptors, Adrenergic, beta-2/agonists. Pharmacology 1997 Apr;54(4):211-24

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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