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Drug Carriers

More information in Books or onNLM PubMed
Definition: Forms to which substances are incorporated to improve the delivery and the effectiveness of drugs. Drug carriers are used in drug-delivery systems such as the controlled-release technology to prolong in vivo drug actions, decrease drug metabolism, and reduce drug toxicity. Carriers are also used in designs to increase the effectiveness of drug delivery to the target sites of pharmacological actions. Liposomes, albumin microspheres, soluble synthetic polymers, DNA complexes, protein-drug conjugates, and carrier erythrocytes among others have been employed as biodegradable drug carriers.  coord with specific drug   
Examples Liposomes; Nanocapsules; Nanoconjugates; Virosomes 		Other names Drug Carrier
Substances having this pharmacologic action: monomethoxypolyethylene glycol; Polyethylene Glycols; Carboxymethylcellulose Sodium
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RV24 peptide  0   *Peptides Drug Carriers. Biochem Biophys Res Commun. 2012 Mar 9;419(2):170-4.
(NP(PEG750)(GlyPheLeu)2Et)3  0   *Peptides *Polyethylene Glycols Drug Carriers. Int J Pharm. 2012 Jan 17;422(1-2):374-80.
monomethoxypolyethyleneglycol-cholesteryl ester  0   *Cholesterol Esters *Polyethylene Glycols Drug Carriers. AAPS PharmSciTech. 2011 Dec;12(4):1056-63.
poly(2-(dimethylamino)ethyl methacrylate)-block-poly(2-(diisopropylamino)ethyl methacrylate)  0   *Polymethacrylic Acids Drug Carriers. ACS Nano. 2011 Nov 22;5(11):9246-55.
polysorbitol-based osmotically active transporter polymer  0   *Polyesters Polyethyleneimine/*analogs & derivatives Drug Carriers Gene Transfer Techniques. Biomaterials. 2011 Dec;32(36):9908-24.
poly(ethylene glycol)-block-poly(propylene sulfide)-block-poly(ethylene imine)  0   *Polyethylene Glycols *Sulfides Polyethyleneimine/*analogs & derivatives Drug Carriers Gene Transfer Techniques. Biomaterials. 2011 Dec;32(36):9839.
star poly(ethylene glycol)hydrazide-prednisolone-20-hydrazone  0   *Polyethylene Glycols Prednisolone/*analogs & derivatives Drug Carriers. Int J Pharm. 2011 Jul 29;414(1-2):42-7.
poly(alpha-methyl-beta-malate)  0   *Polyesters Drug Carriers. Macromol Biosci. 2011 Oct 10;11(10):1370-7.
N-end cysteine peptide tumor-homing peptide  0   *Oligopeptides Drug Carriers. Cancer Cell. 2009 Dec 8;16(6):510-20.
heptakis(6-(2-aminoethylthio)-6-deoxy-2-O-octyloxycarbonylethylsulfanylpropyl)-beta-cyclodextrin  0   *Sulfides *beta-Cyclodextrins Drug Carriers. Org Biomol Chem. 2009 Sep 21;7(18):3763-71.
folate-poly(ethylene glycol)-grafted-trimethyl chitosan  0   *Polyethylene Glycols Chitosan/*analogs & derivatives Drug Carriers. J Drug Target. 2011 Sep;19(8):647-56.
methoxy poly(ethylene glycol)-b-poly(2-hydroxyethyl methacrylate)-co-histidine-poly(lactide)  0   *Polyethylene Glycols *Polymethacrylic Acids Drug Carriers. J Control Release. 2011 Aug 25;154(1):84-92.
cystine-N-carboxy anhydride  0   *Anhydrides Cystine/*analogs & derivatives Drug Carriers. Macromol Biosci. 2011 Jul 7;11(7):962-9.
gamma-benzylglutamyl-N-carboxy anhydride  0   *Anhydrides *Glutamates Drug Carriers. Macromol Biosci. 2011 Jul 7;11(7):962-9.
poly(glycerol adipate-co-omega-pentadecalactone)  0   *Polyesters Drug Carriers. J Microencapsul. 2008 May;25(3):187-95.
R11 peptide  0   *Oligopeptides Drug Carriers. Cancer Res. 2006 Sep 15;66(18):8954-8.
diglyceryl-tetraether  0   *Diglycerides Drug Carriers. Int J Pharm 2011 Aug 30;415(1-2):150-7
glycerylcaldityl-tetraether  0   *Diglycerides *Glycolipids Drug Carriers. Int J Pharm 2011 Aug 30;415(1-2):150-7
poly(omega-pentadecalactone-co-p-dioxanone)  0   *Polyesters Drug Carriers. Biomaterials 2011 Sep;32(27):6646-54
N-benzyl-O-carboxymethylchitosan  0   Chitosan/*analogs & derivatives Drug Carriers. Acta Biomater 2011 Aug;7(8):3078-85
methoxy poly(ethylene glycol)-block-poly(lactic acid)  0   *Polyesters *Polyethylene Glycols Drug Carriers. Cancer Chemother Pharmacol 2011 Aug;68(2):431-44
poly(ethoxytriethyleneglycol acrylate)  0   *Acrylic Resins *Polyethylene Glycols Drug Carriers. J Control Release 2010 Nov 20;148(1):e81-2
(valyl-glutamyl-leucyl-prolyl-prolyl-prolyl)3  0   *Peptides Drug Carriers. Chembiochem 2011 Apr 11;12(6):896-903
poly(2-dimethylaminoethylamine 2-(2-aminoethyoxy)ethoxy)phosphazene  0   *Organophosphorus Compounds *Polymers Drug Carriers. Int J Pharm 2011 Feb 28;405(1-2):188-95
1,2-distigmasterylhemisuccinoyl-glycero-3-phosphocholine  0   *Phosphatidylcholines Stigmasterol/*analogs & derivatives Drug Carriers. Int J Pharm 2011 Apr 15;408(1-2):163-72
chitosan-6-mercaptonicotinic acid  0   *Sulfhydryl Compounds Chitosan/*analogs & derivatives Drug Carriers. Biomacromolecules 2009 Nov 9;10(11):3023-7
poly(3,4-dihydroxycinnamic acid)-co-poly(4-hydroxycinnamic acid)-graft-dithiothreitiol copolymer  0   *Polyesters *Sulfhydryl Compounds Drug Carriers. J Control Release 2011 Jan 20;149(2):182-9
poly(ethylene glycol) methyl ether methacrylate-co-ethylene glycol dimethacrylate  0   *Polymethacrylic Acids Drug Carriers. Nanotechnology 2011 Feb 11;22(6):065604
poly(epsilon-caprolactone)-block-poly(ethyl ethylene phosphate)  0   *Polyesters Drug Carriers. Pharm Res 2010 Dec;27(12):2657-69
poly(ethylene glycol)-b-(epsilon-caprolactone)-b-poly(acrylic acid)  0   *Acrylic Resins *Polyesters Drug Carriers. J Biomed Mater Res A 2011 Feb;96(2):330-40
poly(vinylbenzoate)  0   *Polyvinyls Drug Carriers. J Control Release 2010 Dec 1;148(2):234-40
poly(ethylene glycol)-block-poly(2-methyl-2-carboxylpropylene carbonate-graft-dodecanol)  0   *Polyesters *Polyethylene Glycols Drug Carriers. Biomacromolecules 2010 Oct 11;11(10):2610-20
((2-lactoylamido)ethylamino)formic acid cholesterol ester  0   Cholesterol/*analogs & derivatives Drug Carriers. Yao Xue Xue Bao 2007 May;42(5):538-44
poly(propylene succinate)  0   *Polyesters Drug Carriers. AAPS PharmSciTech 2009;10(1):138-46
mono-6-deoxy-6-oxytocinyl-beta-cyclodextrin 5  0   *Oxytocin *beta-Cyclodextrins Drug Carriers. Bioorg Med Chem Lett 2008 Mar 15;18(6):1855-8
Inutec SP1  0   *Polysaccharides Drug Carriers. Int J Pharm. 2006 Jun 19;316(1-2):1-6
metafectene  0   *Lipids Drug Carriers Liposomes. Mol Biotechnol 2004 Oct;28(2):97-103
poly(N-isopropylacrylamide-co-(dimethylamino)ethylmethacrylate-co-butylmethacrylate)  0   *Acrylic Resins Drug Carriers. J Control Release 2004 Mar 5;95(2):343-55
PEG-methioninase  EC 4.4.1.-   *Polyethylene Glycols *Carbon-Sulfur Lyases Drug Carriers. Adv Exp Med Biol. 2003;519:69-79
N-docosahexaenoyl-O-phospho-2-aminoethanol  0   *Ethanolamines Drug Carriers. Anticancer Res 2002 Nov-Dec;22(6C):4191-8
poly(N-isopropylacrylamide-co-acrylamide)  0   *Acrylic Resins Drug Carriers. Adv Drug Deliv Rev. 2002 Sep 13;54(5):613-30
Eudragit L100-55  0   *Acrylic Resins Drug Carriers. AAPS PharmSci. 2001;3(1):E8
polylysine-graft-(poly(ethylene glycol))  0   *Polyethylene Glycols Polylysine/*analogs & derivatives Drug Carriers. Biomacromolecules 2000 Winter;1(4):523-33
poly(N-(4-(2-(3-benzoylphenyl)propionyloxy)-2-ethoxyphenyl)methacrylamide-co-2-hydroxyethyl methacyrlate)  0   *Methacrylates Drug Carriers. J Biomater Sci Polym Ed 2000;11(12):1429-41
poly(N-(4-(2-hydroxy)ethoxyphenyl)methacrylamide-co-2-hydroxyethyl methacrylate)  0   *Methacrylates Drug Carriers. J Biomater Sci Polym Ed 2000;11(12):1429-41
HN-1 peptide  0   *Oligopeptides Drug Carriers. Cancer Res 2000 Dec 1;60(23):6656-62
peginterferon alfa-2b  0   *Polyethylene Glycols *Interferon-alpha Recombinant Proteins Drug Carriers Hepatitis C.
Pharma Action Antiviral Agents 		Gastroenterol Clin Biol 2000 Aug-Sep;24(8-9):767-9PEGINTRON; SYLATRON; PEGINTRON/REBETOL COMBO PACK
poly(ethylene oxide)-block-poly(2-hydroxyethylaspartamide)  0   *Polyethylene Glycols Aspartic Acid/*analogs & derivatives Drug Carriers Micelles.
poly(ethylene oxide)-block-poly(beta-benzyl aspartate)  0   *Aspartic Acid *Biopolymers *Polyethylene Glycols Drug Carriers. J Biomed Mater Res 2000 Dec 15;52(4):831-5
poly(ethylene oxide)-block-poly(N-hexyl stearate) aspartamide  0   *Polyesters *Polyethylene Glycols Drug Carriers. J Biomed Mater Res 2000 Dec 15;52(4):831-5
poly(ethylene oxide)-block-poly(N-ethyl stearate) aspartamide  0   *Polyesters *Polyethylene Glycols Drug Carriers. J Biomed Mater Res 2000 Dec 15;52(4):831-5
poly(1,6-hexanediisocyanate-co-polycaprolactonediol-co-ciprofloxacin)  0   *Polyesters Ciprofloxacin/*analogs & derivatives Drug Carriers. Biomaterials 2000 Jun;21(12):1235-46
poly(2-(dimethylamino)ethyl methacrylate)  0   *Methacrylates *Nylons Drug Carriers. J Gene Med 1999 Nov-Dec;1(6):407-14
poly(trimellitylimidoglycine-co-sebacic anhydride)-b-polyethylene glycol  0   *Anhydrides *Polyethylene Glycols Delayed-Action Preparations Drug Carriers. Int J Pharm 2000 Jan 20;194(1):51-60
poly(sebacic anhydride)-b-polyethylene glycol  0   *Anhydrides *Polyethylene Glycols Delayed-Action Preparations Drug Carriers. Int J Pharm 2000 Jan 20;194(1):51-60
PLC(20)-b-PEO(44)  0   *Ethylene Oxide *Lactones Drug Carriers Polymers. Biochim Biophys Acta 1999 Sep 21;1421(1) :32-8
chitosan phthalate  0   *Chitosan Drug Carriers. Arch PHarm (Weinheim) 1999 Mar;332(3):103-7
chitosan succinate  0   *Chitosan Drug Carriers. Arch Pharm (Weinheim) 1999 Mar;332(3):103-7
poly(caprolactone-co-6-methyl-2,5-morpholinedione)  0   *Polyamines *Polyesters Drug Carriers. Pharm Dev Technol 1999 Jan;4(1):97-106
poly(lactide-co-6-methyl-2,5-morpholinedione)  0   *Polyamines *Polyesters Drug Carriers. Pharm Dev Technol 1999 Jan;4(1):97-106
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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