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Lactones
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Definition
: Cyclic esters of hydroxy carboxylic acids, containing a 1-oxacycloalkan-2-one structure. Large cyclic lactones of over a dozen atoms are MACROLIDES.
pyran-2-ones: index PYRONES + LACTONES but BENZOPYRAN-2-ONES is available; for cyclic lactones over 12 atoms consider MACROLIDES
Examples
4-Butyrolactone
;
Acetogenins
;
Acyl-Butyrolactones
;
Dehydroascorbic Acid
;
Macrolides
;
Picrotoxin
;
Polyketides
;
Propiolactone
;
Spironolactone
;
Venturicidins
;
Zearalenone
Substance
CAS Registry & name
Categories
Source
Drugs
*
linearifolin
0
*Lactones
*Sesquiterpenes.
Org Lett. 2012 Feb 17;14(4):968-71
zaluzanin A
0
*Lactones
*Sesquiterpenes.
Org Lett. 2012 Feb 17;14(4):968-71
saccharic acid-
1,4-
lactone
0
*Lactones.
Anal Biochem. 1983 Apr 15;130(2):420-6.
ballonigrin lactone A
0
*Diterpenes
*Lactones.
Nat Prod Commun. 2012 Feb;7(2):149-50
ballonigrin lactone B
0
*Diterpenes
*Lactones.
Nat Prod Commun. 2012 Feb;7(2):149-50
2-
oxo-
6-
deoxyneomajucin
0
*Lactones
*Sesquiterpenes.
Yao Xue Xue Bao. 2010 Mar;45(3):330-3
6-
deoxyneomajucin
0
*Lactones
*Sesquiterpenes.
Yao Xue Xue Bao. 2010 Mar;45(3):330-3
lyngbouilloside aglycon
0
*Lactones
*Macrolides.
Org Lett. 2012 Jan 6;14(1):314-7
eupalinolide A
0
*Lactones
*Sesquiterpenes, Germacrane.
Biochem Pharmacol. 2012 Apr 1;83(7):909-22
eupalinolide B
0
*Lactones
*Sesquiterpenes, Germacrane.
Biochem Pharmacol. 2012 Apr 1;83(7):909-22
amberin
0
*Lactones
*Sesquiterpenes.
Asian Nat Prod Res. 2012;14(3):281-5
carlactone
0
*Lactones.
Science. 2012 Mar 16;335(6074):1348-51
cerinolactone
0
*Lactones
Antifungal Agents.
J Nat Prod. 2012 Jan 27;75(1):103-6
10-
O-
dimethylaminoethylginkgolide B
0
*Lactones
*Ginkgolides
Cardiotonic Agents.
J Asian Nat Prod Res. 2012;14(1):27-38
lachnone C
0
*Chromones
*Lactones.
Chemistry. 2011 Dec 2;17(49):13706-11
3-
hydroxypterolactone
0
*Lactones.
Fitoterapia. 2011 Oct;82(7):1081-5
sausinlactone C
0
*Lactones
*Sesquiterpenes.
Fitoterapia. 2011 Oct;82(7):983-7
sausinlactone B
0
*Lactones
*Sesquiterpenes.
Fitoterapia. 2011 Oct;82(7):983-7
sausinlactone A
0
*Lactones
*Sesquiterpenes.
Fitoterapia. 2011 Oct;82(7):983-7
ER 813010
0
*Lactones.
Cancer Chemother Pharmacol. 2012 Jan;69(1):229-37.
vicanicin
0
*Lactones
*Depsides.
Chem Biol Interact. 2012 Jan 5;195(1):18-24.
2'-
O-
methylhypostictic acid
0
*Lactones
*Depsides.
J Asian Nat Prod Res. 2011 Dec;13(12):1158-64
myrolactone B
0
*Lactones.
J Asian Nat Prod Res. 2011 Oct;13(11):1003-7
myrolactone A
0
*Lactones.
J Asian Nat Prod Res. 2011 Oct;13(11):1003-7
chloranthalactone A
0
*Heterocyclic Compounds with 4 or More Rings
*Lactones.
Org Lett. 2011 Oct 7;13(19):5406-8
ecklonialactone C
0
*Lactones.
J Am Chem Soc. 2011 Aug 31;133(34):13471-80
massarigenin A
0
*Lactones
*Spiro Compounds.
Chirality. 2011 Sep;23(8):617-23
gelomulide K
0
*Diterpenes
*Lactones.
Free Radic Biol Med. 2011 Aug 1;51(3):641-57.
psilostachyin A
0
*Lactones
*Sesquiterpenes.
Planta Med. 2005 Oct;71(10):938-43.
maldoxin
0
*Lactones
*Spiro Compounds.
Org Lett. 2011 Aug 19;13(16):4224-7
ixerin N 6'-
O-
acetate
0
*Lactones
*Sesquiterpenes.
Planta Med. 2011 Mar;77(4):380-2
ixerisoside A
0
*Lactones
*Sesquiterpenes.
Planta Med. 2011 Mar;77(4):380-2
3beta,8beta-
dihydroxy-
guaia-
10(14)-
en-
1alpha,4alpha,5alpha,6beta,7alpha,11betaH-
12,6alpha-
olide
0
*Lactones
*Sesquiterpenes.
Planta Med. 2011 Mar;77(4):380-2
2'-
isopicrasin A
0
*Lactones
*Sesterterpenes.
Chem Biodivers 2011 Jun;8(6):1163-9
ixerin Z2
0
*Lactones
*Sesquiterpenes.
Nat Prod Commun. 2011 Aug;6(8):1055-7
ceestatin
0
*Lactones
*Bicyclo Compounds, Heterocyclic
Hydroxymethylglutaryl-CoA Synthase/antagonists & inhibitors.
J Infect Dis 2011 Aug;204(4):609-16
deacylcynaropicrin
31565-50-1
*Lactones
*Sesquiterpenes.
Pharm Biol. 2011 Jul;49(7):675-8
spiro-
prorocentrimine
0
*Lactones
*Spiro Compounds.
Org Lett. 2011 Jul 15;13(14):3758-61
lactodehydrothyrsiferol
0
*Lactones
*Pyrans.
Angew Chem Int Ed Engl. 2011 May 23;50(22):5178-81
plakortone E
0
*Lactones.
Chemistry. 2011 May 16;17(21):5874-80
cochliomycin C
0
*Hydroxybenzoic Acids
*Lactones.
J Nat Prod. 2011 Apr 25;74(4):629-33
cochliomycin B
0
*Hydroxybenzoic Acids
*Lactones.
J Nat Prod. 2011 Apr 25;74(4):629-33
cochliomycin A
0
*Hydroxybenzoic Acids
*Lactones.
J Nat Prod. 2011 Apr 25;74(4):629-33
eremophila-
1(10)-
11(13)-
dien-
12,8-
olide
0
*Lactones
*Sesquiterpenes.
J Exp Clin Cancer Res 2011;30:29
lecythomycin
0
*Lactones
*Mannosides.
Nat Prod Commun. 2011 May;6(5):677-8
antrocin
0
*Lactones
*Sesquiterpenes
TOR Serine-Threonine Kinases/antagonists & inhibitors.
Chem Res Toxicol. 2011 Feb 18;24(2):238-45
neojaponicone A
0
*Lactones
*Sesquiterpenes.
Chem Commun (Camb). 2011 Jan 28;47(4):1222-4
ficusmicrochlorin C
0
*Lactones.
Chem Pharm Bull (Tokyo). 2011;59(1):113-6
ficusmicrochlorin B
0
*Lactones.
Chem Pharm Bull (Tokyo). 2011;59(1):113-6
ficusmicrochlorin A
0
*Lactones.
Chem Pharm Bull (Tokyo). 2011;59(1):113-6
TAN-
2483B
0
*Lactones
*Pyrans.
Org Biomol Chem. 2011 Feb 21;9(4):998-1000
pectenotoxin 11
0
*Lactones
*Pyrans.
Chem Commun (Camb). 2011 Jan 7;47(1):259-61
anislactone A
0
*Lactones
*Sesquiterpenes.
Angew Chem Int Ed Engl. 2010 Nov 22;49(48):9250-3
pestalalactone
0
*Benzophenones
*Lactones.
Angew Chem Int Ed Engl. 2010 Oct 4;49(41):7588-91
pochoxime A
0
*Lactones
*Oximes
HSP90 Heat-Shock Proteins/antagonists & inhibitors.
Chembiochem 2009 Nov 23;10(17):2753-9
herbaric acid
0
*Heterocyclic Compounds, 2-Ring
*Lactones.
J Org Chem. 2010 Nov 5;75(21):7388-92
plakortone F
0
*Lactones.
J Org Chem. 2010 Oct 1;75(19):6489-501
plakortone C
0
*Lactones.
J Org Chem. 2010 Oct 1;75(19):6489-501
6-
(4-
hydroxy-
6-
phenylhex-
2-
enyl)-
5,6-
dihydropyran-
2-
one
0
*Lactones
*Pyrones.
Eur J Med Chem 2010 Oct;45(10):4657-63
uprolide D
0
*Bridged Compounds
*Lactones.
Org Lett. 2010 Oct 1;12(19):4328-31
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