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TOR Serine-Threonine Kinases

More information in Books or onNLM PubMed
Definition: A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that TACROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.      Other names mTOR Serine Threonine Kinases; Target Protein, Rapamycin; TOR Serine Threonine Kinases; Serine-Threonine Kinases, mTOR; Serine-Threonine Kinases, TOR; Rapamycin Proteins Target; RAFT 1 Protein; Protein, mTOR; Protein, Rapamycin Target; Protein, RAFT-1; Protein, FKBP12-Rapamycin Complex-Associated; Protein, FKBP12-Rapamycin Associated; Kinases, mTOR Serine-Threonine; Kinases, TOR Serine-Threonine; FKBP12 Rapamycin Complex Associated Protein; FKBP12 Rapamycin Associated Protein; FK506 Binding Protein 12 Rapamycin Associated Prot; Complex-Associated Protein, FKBP12-Rapamycin; Associated Protein, FKBP12-Rapamycin; mTOR Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
antrocin  0   *Lactones *Sesquiterpenes TOR Serine-Threonine Kinases/antagonists & inhibitors. Chem Res Toxicol. 2011 Feb 18;24(2):238-45
DEP domain-containing and mTOR-interacting protein, human  EC 2.7.1.1   *TOR Serine-Threonine Kinases. Cell 2009 May 29;137(5):873-86
mTOR protein, rat  EC 2.7.1.1   *TOR Serine-Threonine Kinases.
mTOR protein, mouse  EC 2.7.1.1   *TOR Serine-Threonine Kinases.
MTOR protein, human  EC 2.7.1.1   *TOR Serine-Threonine Kinases.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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