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Lyngbya Toxins

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Definition: Toxins isolated from any species of the seaweed Lyngbya or similar chemicals from other sources, including mollusks and micro-organisms. These have been found to be potent tumor promoters. They are biosynthesized from TRYPTOPHAN; VALINE; and METHIONINE nonribosomally (PEPTIDE BIOSYNTHESIS, NUCLEIC ACID-INDEPENDENT).  /antag permitted but consider also ANTITOXINS; coordinate with source only if particularly discussed   
Pharmacological Action Poisons 		Other names Toxins, Lyngbya
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
lyngbyabellin C  0   *Lyngbya Toxins *Thiazoles. ACS Chem Biol 2011 May 20;6(5):425-31
nhatrangin B  0   *Lyngbya Toxins. J Nat Prod. 2010 Apr 23;73(4):784-7
nhatrangin A  0   *Lyngbya Toxins. J Nat Prod. 2010 Apr 23;73(4):784-7
desacetylmicrocolin B  0   *Oligopeptides *Pyrrolidines Lyngbya Toxins. Planta Med. 2009 Oct;75(13):1427-30
pahayokolide B  0   *Lyngbya Toxins *Peptides, Cyclic. J Nat Prod 2007 May;70(5):730-5
pahayokolide A  0   *Lyngbya Toxins *Peptides, Cyclic. Comp Biochem Physiol C Toxicol Pharmacol 2004 Dec;139(4):231-8
lyngbyabellin D  0   *Lyngbya Toxins *Thiazoles. J Nat Prod 2003 May;66(5):595-8
15-norlyngbyapeptin A  0   *Lyngbya Toxins *Thiazoles. J Nat Prod 2003 May;66(5):595-8
lyngbyabellin B  0   *Lyngbya Toxins *Thiazoles *Depsipeptides. J Nat Prod. 2000 Oct;63(10):1437-9
lyngbyapeptin A  0   *Lyngbya Toxins *Thiazoles. J Nat Prod. 2000 Oct;63(10):1437-9
manauealide B  0   *Lyngbya Toxins. J Nat Prod 1997 Sep;60(9):925-8
lyngbyatoxin C  133084-53-4 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 9-(1-ethenyl-5-hydroxy-1,5-dimethyl-3-hexenyl)-1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)-, (2S-(2R*,5R*,9(S*)))  *Lyngbya Toxins Dermotoxins Marine Toxins. J Nat Prod 1990;53(6):1593
lyngbyatoxin B  133084-52-3 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 9-(1-ethenyl-4-hydroxy-1,5-dimethyl-5-hexenyl)-1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)  *Lyngbya Toxins Dermotoxins Marine Toxins. J Nat Prod 1990;53(6):1593
26-(2'-aminoethylthio)tetrahydroteleocidin A-2  117490-45-6   *Lyngbya Toxins Haptens. Carcinogenesis 1988;9(9):1629
des-O-methylolivoretin C  95013-42-6   *Lyngbya Toxins. Jpn J Cancer Res l986;77(3):222
olivoretin  90297-52-2   *Lyngbya Toxins. Gann 1984;75(10):837
dihydroteleocidin B  7491-76-1   *Lyngbya Toxins.
Pharma Action Carcinogens ; Irritants 		Biochem Biophys Res Commun 90(3):976;1979
teleocidin  78474-55-2 6H-Benzo(g)(1,4)diazonino(7,6,5-cd)indol-6-one, 13-ethenyl-1,3,4,5,7,8,10,11,12,13-decahydro-4-(hydroxymethyl)-8,10,13-trimethyl-7,10-bis(1-methylethyl)-, (4S-(4R*,7R*,10S*,13S*))  *Lyngbya Toxins.
Pharma Action Carcinogens ; Irritants 		Biochem Biophys Res Commun 90(3):976;1979
lyngbyatoxin A  70497-14-2 3H-Pyrrolo(4,3,2-gh)-1,4-benzodiazonin-3-one, 9-(1-ethenyl-1,5-dimethyl-4-hexenyl)-1,2,4,5,6,8-hexahydro-5-(hydroxymethyl)-1-methyl-2-(1-methylethyl)  *Lyngbya Toxins Dermotoxins Marine Toxins. Science 204(4039):193;1979
debromoaplysiatoxin  52423-28-6   *Lyngbya Toxins Seaweed.
Pharma Action Carcinogens 		Arch Dermatol 114(9):1333;1978
aplysiatoxin  52659-57-1   *Lyngbya Toxins. J Am Chem Soc 96(7):2245;1974; J Nat Products 38(1):1;1975

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