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Glycine

More information in Books or onNLM PubMed
Definition: A non-essential amino acid. It is found primarily in gelatin and silk fibroin and used therapeutically as a nutrient. It is also a fast inhibitory neurotransmitter.     
Pharmacological Action Glycine Agents
See Also Receptors, Glycine
Examples Allylglycine; N-substituted Glycines 		Other names Aminoacetic Acid; Salt Glycine, Monosodium; Salt Glycine, Monoammonium; Phosphate, Glycine; Monosodium Salt Glycine; Monopotasssium Salt Glycine; Monoammonium Salt Glycine; Hydrochloride, Glycine; Copper Salt Glycine; Cobalt Salt Glycine; Calcium Salt Glycine; Acid, Aminoacetic; Glycine, Sodium Hydrogen Carbonate; Glycine, Monosodium Salt; Glycine, Monopotasssium Salt; Glycine, Monoammonium Salt; Glycine, Copper Salt; Glycine, Cobalt Salt; Glycine, Calcium Salt (2:1); Glycine, Calcium SaltDrugs* : GLYCINE 1.5% IN PLASTIC CONTAINER; AMINOACETIC ACID 1.5% IN PLASTIC CONTAINER
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(1-(4-(4-methoxybenzyl)-5-phenethyl-4H-1,2,4-triazol-3-yl)-2-(1H-indol-3-yl)ethyl)-2-aminoacetamide  0   *Triazoles Glycine/*analogs & derivatives. Eur J Pharmacol. 2009 Jun 10;612(1-3):167-73.
N-(2-(triphenylmethyl)thioethyl)-3-aza-19-ethyloxycarbonyl-3-(2-(triphenylmethyl)thioethyl)octadecanoate  0   *Palmitic Acids Glycine/*analogs & derivatives Ligands. Nucl Med Biol. 2011 Oct;38(7):1043-52.
GPGPGP peptide  0   *Oligopeptides Glycine/*analogs & derivatives Proline/*analogs & derivatives. Eksp Klin Gastroenterol. 2011;(5):53-5
glycinium semi-malonate  0   Glycine/*analogs & derivatives. Acta Crystallogr C. 2011 Aug;67(Pt 8):o297-300
glutaric acid-glycine  0   *Glutarates Glycine/*analogs & derivatives. Acta Crystallogr C. 2011 Aug;67(Pt 8):o297-300
N-myristoylated-methyl-glycine  0   Glycine/*analogs & derivatives. J Phys Chem B. 2011 May 12;115(18):5294-303
CHR-79888  0   *Hydroxamic Acids Glycine/*analogs & derivatives. Leuk Res. 2011 May;35(5):677-81
N-(p-toluenesulfonyl)-(R)-phenylglycine  0   Glycine/*analogs & derivatives. Chirality. 2011 Apr;23(4):326-32
2-(((4-methoxyphenoxy)carbonyl)(1-(4-(2-(5-methyl-2-phenyloxazol-4-yl)ethoxy)phenyl)ethyl)amino)acetic acid  0   *Oxazoles Glycine/*analogs & derivatives PPAR alpha/agonists PPAR gamma/agonists. Drug Metab Dispos 2011 Feb;39(2):228-38
(((5-(1,1-dimethylethyl)thiazol-2-yl)methyl)(((4-(4-(4-(1-propylbutyl)phenoxy)methyl)phenyl)thiazol-2-yl)methyl)amino)acetic acid  0   *Thiazoles Glycine/*analogs & derivatives Protein Tyrosine Phosphatase, Non-Receptor Type 1/antagonists & inhibitors. Diabetes Obes Metab 2010 Apr;12(4):299-306
3-(trifluoromethyl)bicyclopent-(1.1.1)-1-yl glycine  0   *Bicyclo Compounds Glycine/*analogs & derivatives. Amino Acids 2010 Nov;39(5):1589-93
1-methyl-5-p-methylbenzoylpyrrol-2-acetamidoacetic acid  0   Glycine/*analogs & derivatives Tolmetin/*analogs & derivatives. Biomed Chromatogr 2010 Oct;24(10):1100-7
N-((1-(cyclopropylethyl)-6-fluoro-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinyl)carbonyl)glycine  0   *Quinolones Glycine/*analogs & derivatives. J Cardiovasc Pharmacol 2010 Aug;56(2):147-55
4-formylaminooxyvinylglycine  0   Glycine/*analogs & derivatives Herbicides Plant Weeds/drug effects. J Nat Prod. 2010 Nov 29;73(11):1853-7
2-(2-((2-hydroxybenzyl)amino)ethylamino)-2-(2-hydroxyphenyl)acetic acid  0   *Benzylamines Glycine/*analogs & derivatives. J Agric Food Chem 2010 Jul 14;58(13):7908-14
homopropargylglycine  0   *Alkynes Glycine/*analogs & derivatives. Biochemistry 2002 Aug 27;41(34):10635-45
deoxyadenosine monophosphate iminodiacetic acid phosphoramidate  0   Adenosine Monophosphate/*analogs & derivatives Glycine/*analogs & derivatives. Nucleic Acids Res 2010 May 1;38(8):2541-50
2-((3-((2-(4-chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic acid  0   *Oxazoles Glycine/*analogs & derivatives PPAR alpha/agonists. J Med Chem 2010 Apr 8;53(7):2854-64
ureidoglycine  0   Glycine/*analogs & derivatives Urea/*analogs & derivatives. ACS Chem Biol 2010 Feb 19;5(2):203-14
N-(2-naphthalenyl)-((3,5-dibromo-2,4-dihydroxyphenyl)methylene)glycine hydrazide  0   *Hydrazines Glycine/*analogs & derivatives. J Pharmacol Exp Ther 2010 Apr;333(1):60-9
MLN 9708  0   *Boron Compounds Glycine/*analogs & derivatives. Cancer Res 2010 Mar 1;70(5):1970-80
2-indanylglycine  0   *Indans Glycine/*analogs & derivatives. J Pept Sci 2010 Jan;16(1):15-20
N-nicotinoyl-2-(2-(2-methyl-5-nitroimidazol-1-yl)ethyloxy)-D,L-glycine  0   Glycine/*analogs & derivatives Metronidazole/*analogs & derivatives. J Pharm Sci. 2009 Nov;98(11):4161-9
7-(2-(bis-carboxymethyl-amino)ethyl)-4,10-bis-carboxymethyl-1,4,7,10-tetraazacyclododec-1-yl-acetic acid  0   *Heterocyclic Compounds, 1-Ring Glycine/*analogs & derivatives. Bioorg Med Chem Lett 2008 Nov 1;18(21):5792-5
N2-(4-nitrophenyl)-N1-propylglycinamide  0   Glycine/*analogs & derivatives. Bioorg Med Chem. 2009 Nov 1;17(21):7449-56
N-(2-carboxyphenyl)glycine  0   *Anthranilic Acids Glycine/*analogs & derivatives. J Phys Chem A 2009 Jun 18;113(24):6562-71
N-trichloroethoxycarbonyl glycine  0   Glycine/*analogs & derivatives. J Am Chem Soc. 2009 Apr 29;131(16):5746-7
Iminoglycinuria  0   *Renal Tubular Transport, Inborn Errors Glycine/urine.
3,5-dinitrobenzoylglycine  0   *Dinitrobenzenes Glycine/*analogs & derivatives. Anal Bioanal Chem 2009 Jan;393(1):303-12
bisglycinehydrogenchloride  0   Glycine/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc. 2008 Nov 1;71(1):119-24
tosedostat  238750-77-1   *Hydroxamic Acids Glycine/*analogs & derivatives. Cancer Res 2008 Aug 15;68(16):6669-79
N-(2-methylbenzylidene)-phenylglycine amide  0   *Amides *Benzyl Compounds Glycine/*analogs & derivatives. Angew Chem Int Ed Engl. 2008;47(34):6445-7
(4-carboxymethyl-7-(2-(carboxymethylamino)-3-(4-nitrophenyl)propyl)(1,4,7)triazonan-1-yl)acetic acid  0   *Heterocyclic Compounds, 1-Ring Glycine/*analogs & derivatives. Bioconjug Chem 2008 Jul;19(7):1439-47
(4-(2-(biscarboxymethylamino)-3-(4-nitrophenyl)propyl)-7-carboxymethyl(1,4,7)triazonan-1-yl)acetic acid  0   *Heterocyclic Compounds, 1-Ring Glycine/*analogs & derivatives. Bioconjug Chem 2008 Jul;19(7):1439-47
N-hydroxysuccinimidyl S-acetylmercaptoacetyltriglycline  0   *Succinimides Glycine/*analogs & derivatives. World J Gastroenterol. 2008 Apr 14;14(14):2235-40
cocoamphodiacetic acid  0   *Acetic Acids Glycine/*analogs & derivatives. J Environ Sci Health A Tox Hazard Subst Environ Eng 2001 Sep;36(8):1451-71
tricholomic acid  0   *Isoxazoles Glycine/*analogs & derivatives Receptors, AMPA/agonists Receptors, Kainic Acid/agonists Receptors, Metabotropic Glutamate/agonists. J Med Chem 2008 Apr 10;51(7):2311-5
glycylcholesteryl formylhydrazide  0   Cholesterol/*analogs & derivatives Glycine/*analogs & derivatives. Drug Deliv 2008 Feb;15(2):97-105
GW791343  0   *Piperazines Glycine/*analogs & derivatives. Br J Pharmacol 2008 Feb;153(4):737-50
trans-bis(glycine)nickel(II)  0   *Organometallic Compounds Glycine/*analogs & derivatives Nickel. Spectrochim Acta A Mol Biomol Spectrosc. 2007 Dec 31;68(5):1370-8
aminoethylglycyl PNA  0   *Peptide Nucleic Acids Glycine/*analogs & derivatives. Nucleosides Nucleotides Nucleic Acids. 2007;26(10-12):1307-10
(4-(2-(bis(carboxymethyl)amino)-3-(4-nitrophenyl)propyl)-7-carboxymethyl(1,4,7)triazanonan-1-yl)acetic acid  0   *Heterocyclic Compounds, 1-Ring Glycine/*analogs & derivatives Ligands. J Med Chem 2008 Jan 10;51(1):118-25
alpha-ethyl-N-(phosphonomethyl)glycine  0   *Phosphonic Acids Glycine/*analogs & derivatives. Amino Acids 2007 Nov;33(4):695-702
C(alpha)-formylglycine  5735-66-0 (2S)-2-amino-3-oxopropanoic acid  *Alanine/analogs & derivatives *Glycine/analogs & derivatives Sulfatases.
N,N'-ethylenebis(2-(o-hydroxyphenolic)glycine)  0   Glycine/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc 2007 Sep;68(1):165-8
acetyl-N-methyl-glycine  0   Glycine/*analogs & derivatives. Phys Chem Chem Phys 2007 Sep 7;9(33):4698-708
N-((3beta)-3-(acetyloxy)-28-oxoolean-12-en-28-yl)glycine methyl ester  0   Glycine/*analogs & derivatives Oleanolic Acid/*analogs & derivatives. J Pharm Pharmacol 2007 Aug;59(8):1087-93
palythine  0   *Cyclohexanols Glycine/*analogs & derivatives. Vision Res 1993 Feb;33(3):289-300
oleoylglycine  0   *Oleic Acids Glycine/*analogs & derivatives Fatty Acids. J Biol Chem 2007 Aug 3;282(31):22364-9
(7-hydroxycoumarin-4-yl) ethylglycine  0   *Umbelliferones Glycine/*analogs & derivatives. J Am Chem Soc 2006 Jul 12;128(27):8738-9
phenylglycine hydrazide  0   *Hydrazines Glycine/*analogs & derivatives. Spectrochim Acta A Mol Biomol Spectrosc 2007 May;67(1):172-7
boroglycine  0   *Boron Compounds Glycine/*analogs & derivatives. J Phys Chem A 2007 Jul 19;111(28):6489-500
dimethylthetin  0   Betaine/*analogs & derivatives Glycine/*analogs & derivatives. Exp Toxicol Pathol 2007 Apr;58(5):285-90
(2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine  0   *Cyclopropanes Glycine/*analogs & derivatives. Bioorg Med Chem 2007 May 1;15(9):3161-70
7-(N,N-diethylamino)-4-(hydroxymethyl)coumarin methyl-N-tert-Boc-glycine  0   *Coumarins Glycine/*analogs & derivatives.
sodium N-(11-acrylamidoundecanoyl)-glycinate  0   *Acrylamides Glycine/*analogs & derivatives. Langmuir. 2005 Nov 8;21(23):10362-9
di-mu-hydroxybis(diglycinate)cobalt(III)  0   *Organometallic Compounds Glycine/*analogs & derivatives Cobalt. Spectrochim Acta A Mol Biomol Spectrosc 2006 Dec;65(5):1112-9
N-acetylaminoacetic acid 3-dimethoxyphosphoryl-2-hydroxy-1-propyl ester  0   Glycine/*analogs & derivatives. Eksp Klin Farmakol. 2006 Nov-Dec;69(6):24-6
N-oleoylglycine  0   *Oleic Acids Glycine/*analogs & derivatives. Biochemistry 1999 Mar 16;38(11):3235-45
6-(2-hydroxy-3,4-dioxo-1-cyclobutenyl)-3,6,10-triazadodecane-3,10-tetraacetic acid  0   *Cyclobutanes Glycine/*analogs & derivatives. Dalton Trans 2006 Nov 21;(43):5149-55
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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